Nicotinic Acid EP Impurity C HCl CAS 2024-89-7
| CAS No. | 2024-89-7 |
| Molecular Formula | C8H11N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Nicotinic Acid EP Impurity C HCl.
As a process- or degradation-related impurity, Nicotinic Acid EP Impurity C HCl (CAS 2024-89-7, C8H11NHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C8H11NHCl, Nicotinic Acid EP Impurity C HCl contains a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 157.64 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Nicotinic Acid EP Impurity C HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H11N HCl |
| Molecular Weight | 157.64 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Nicotinic Standards
- Nicotinic Acid EP Impurity D (CAS 100-26-5)
- Nicotinic acid 2-bromo-benzyl ester (CAS 1033692-94-2)
- Nicotinic Acid EP Impurity C (CAS 104-90-5)
- Nicotinic Acid Methyl Ester 5-N-Methylnitrone (CAS 1159977-53-3)
- Nicotinic Acid-d1 (CAS 116975-14-5)
- Nicotinic Acid-13C6,d4 N-Hydroxysuccinimide Ester (CAS 1209457-55-5)
- Nicotinic Acid-13C6,d4 (CAS 1216798-74-1)
- Nicotinic acid 4-formyl-phenyl ester (CAS 15131-72-3)
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