Etoricoxib impurity 70 CAS 202409-40-3

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.202409-40-3
Molecular FormulaC18H15ClN2O2S
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Etoricoxib impurity 70 CAS 202409-40-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Etoricoxib impurity 70.

Etoricoxib impurity 70 (CAS 202409-40-3) is a certified pharmaceutical impurity reference standard with the molecular formula C18H15ClN2O2SHCl and a molecular weight of 395.30 g/mol.

Based on its molecular formula C18H15ClN2O2SHCl, Etoricoxib impurity 70 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 395.30 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Etoricoxib impurity 70 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC18H15ClN2O2S HCl
Molecular Weight395.30 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2014
Halogen ContentCl-containing
Nitrogen Atoms2
Sulfur Atoms1

Related Etoricoxib Standards

Recommended Standards

Why CATO?