Butylphthalide Impurity N2 CAS 20320-37-0
| CAS No. | 20320-37-0 |
| Molecular Formula | C10H11NO3 |
| Molecular Weight | 193.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 193.19 g/mol gives Butylphthalide Impurity N2 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Butylphthalide Impurity N2 (CAS 20320-37-0, C10H11NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Butylphthalide Impurity N2 (C10H11NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11NO3 |
| Molecular Weight | 193.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 1 |
Related Butylphthalide Standards
- 3-Butylphthalide-d3 (CAS 6066-49-5（Unlabelled）)
- Butylphthalide Impurity 32 (CAS 60510-95-4)
- Butylphthalide Impurity 46 (CAS 26311-42-2)
- Butylphthalide Impurity 80 (CAS CATO-C4X-181380)
- Butylphthalide Impurity 9 (CAS 19666-03-6)
- Butylphthalide Impurity 41 (CAS 3413-15-8)
- Butylphthalide Impurity 23 (CAS 199736-94-2)
- Butylphthalide Impurity 35 (CAS 16692-58-3)
Recommended Standards
- Tris(2-cyanoethyl)phosphine (CAS 4023-53-4)
- Bz-D-Ala-OH (CAS 17966-60-8)
- rel-((6R,8aR)-3,3-Difluorohexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-6-yl)methanol (CAS 2850327-08-9)
- For-Phe-OH (CAS 13200-85-6)
- Dotinurad Impurity 258 (CAS CATO-C4X-2494258)
- Ubidecarenone impurity 20 (CAS 2538402-20-7)
- Buspirone EP Impurity H (CAS 2708578-34-9)
- (2S,3R)-3-(((Benzyloxy)carbonyl)amino)-2-hydroxy-4-phenylbutanoic acid(relative) (CAS 76498-22-1)
- Tert-butyl (R)-(1-amino-3-methylbutan-2-yl)carbamate (CAS 400652-50-8)
- 1-(Tetrahydro-2H-pyran-2-yl)-5-(trifluoromethyl)-1H-indazol-4-amine (CAS 2044703-06-0)
- (R)-2-Fluoro-1-phenylethanol (CAS 82255-41-2)
- Ethyl 1-oxiranylmethylisonipecotate (CAS 187084-47-5)
- 5-Bromo-2-(3,5-dimethylphenoxy)aniline (CAS 946700-26-1)
- Macrophage Inhibitory Peptide (CAS 41961-56-2)
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