5-(4-Chlorophenyl)-1,3,4-oxadiazole-2-thiol CAS 203268-67-1
| CAS No. | 203268-67-1 |
| Molecular Formula | C8H5ClN2OS |
| Molecular Weight | 212.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(4-Chlorophenyl)-1,3,4-oxadiazole-2-thiol (CAS 203268-67-1), molecular formula C8H5ClN2OS and molecular weight 212.66 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(4-Chlorophenyl)-1,3,4-oxadiazole-2-thiol (C8H5ClN2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(4-Chlorophenyl)-1,3,4-oxadiazole-2-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5ClN2OS |
| Molecular Weight | 212.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2015 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 3-(3-Chlorophenyl)-1,2,4-thiadiazol-5(4H)-one (CAS 1206969-12-1)
- 3-(2-chlorophenyl)-1,2,4-oxadiazole-5-thiol (CAS 1339372-88-1)
- 3-(4-Chlorophenyl)-1,2,4-thiadiazol-5(4H)-one (CAS 192817-66-6)
- 1-(3-Chlorophenyl)-1H-tetrazole-5-thiol (CAS 22384-88-9)
- 1-(4-Chlorophenyl)-1H-1,2,3,4-tetrazole-5-thiol (CAS 27143-76-6)
- 3-(2-Chlorophenyl)-1,2,4-thiadiazol-5(4H)-one (CAS 691840-21-8)
- 5-(2-Chlorophenyl)-1,3,4-oxadiazole-2-thiol (CAS 23766-27-0)
- 5-(3-Chlorophenyl)-1,3,4-oxadiazole-2(3H)-thione (CAS 41491-54-7)
Recommended Standards
- 5-(4-Chlorophenyl)-1,3,4-thiadiazol-2(3H)-one (CAS 84352-95-4)
- 5-(2-Chloropyridin-4-yl)-1,3,4-thiadiazol-2-amine (CAS 474327-26-9)
- 5-Chloro-1,3-benzoxazole-2-carbothioamide (CAS 33653-00-8)
- 6-(5-Chlorothiophen-2-yl)pyridazin-3-ol (CAS 75792-70-0)
- 1,3-dimethyl-2-oxo-benzimidazole-5-sulfonyl chloride (CAS 24134-65-4)
- 4,6-Diiodo-2-methoxypyrimidine (CAS 164738-58-3)
- 6-Fluoro-2,3-dihydrobenzofuran (CAS 1072153-65-1)
- tert-Butyl 1,5-dimethyl-1H-pyrazole-4-carboxylate (CAS 1337864-17-1)
- 2-Chloro-3-cyclopropoxy-6-methylpyridine (CAS 1243473-43-9)
- 2-(3-Carboxypropyl)benzoic acid (CAS 1081-27-2)
- Prasugrel EP Impurity C (CAS 1391194-50-5)
- (3-Amino-2,6-difluorophenyl)(5-iodo-1H-pyrrolo[2,3-b]pyridin-3-yl)methanone (CAS 1254567-35-5)
- N-(3-Amino-5-cyclopropoxypyridin-4-yl)methanesulfonamide (CAS 1243396-30-6)
- Semaglutide impurity 27 (CAS CATO-C4X-222627)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com