5-(3-Chlorophenyl)-1,3,4-oxadiazole-2(3H)-thione CAS 41491-54-7
| CAS No. | 41491-54-7 |
| Molecular Formula | C8H5ClN2OS |
| Molecular Weight | 212.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(3-Chlorophenyl)-1,3,4-oxadiazole-2(3H)-thione (CAS 41491-54-7), molecular formula C8H5ClN2OS and molecular weight 212.66 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-(3-Chlorophenyl)-1,3,4-oxadiazole-2(3H)-thione (C8H5ClN2OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 212.66 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(3-Chlorophenyl)-1,3,4-oxadiazole-2(3H)-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5ClN2OS |
| Molecular Weight | 212.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 3-(3-Chlorophenyl)-1,2,4-thiadiazol-5(4H)-one (CAS 1206969-12-1)
- 3-(2-chlorophenyl)-1,2,4-oxadiazole-5-thiol (CAS 1339372-88-1)
- 3-(4-Chlorophenyl)-1,2,4-thiadiazol-5(4H)-one (CAS 192817-66-6)
- 1-(3-Chlorophenyl)-1H-tetrazole-5-thiol (CAS 22384-88-9)
- 1-(4-Chlorophenyl)-1H-1,2,3,4-tetrazole-5-thiol (CAS 27143-76-6)
- 3-(2-Chlorophenyl)-1,2,4-thiadiazol-5(4H)-one (CAS 691840-21-8)
- 5-(2-Chlorophenyl)-1,3,4-oxadiazole-2-thiol (CAS 23766-27-0)
- 5-(4-Chlorophenyl)-1,3,4-oxadiazole-2-thiol (CAS 203268-67-1)
Recommended Standards
- 5-(2-Chloropyridin-4-yl)-1,3,4-thiadiazol-2-amine (CAS 474327-26-9)
- 5-(4-Chlorophenyl)-1,3,4-thiadiazol-2(3H)-one (CAS 84352-95-4)
- 4-Chloro-2-(1,2,3-thiadiazol-4-yl)phenol (CAS 847468-22-8)
- 5-Chloro-1,3-benzoxazole-2-carbothioamide (CAS 33653-00-8)
- 2-{6-amino-5-methylimidazo[1,2-a]pyridin-2-yl}acetic acid (CAS 2166871-93-6)
- 4-(4-Oxopiperidin-1-yl)benzonitrile (CAS 79421-46-8)
- tert-butyl 3-oxo-1,2,3,6-tetrahydropyridine-1-carboxylate (CAS 156496-89-8)
- 3(2H)-Pyridazinone (CAS 504-30-3)
- Methyl 5-chloro-2-(dibromomethyl)-4-nitrobenzoate (CAS 143034-84-8)
- Itopride Impurity 27 (CAS CATO-C4X-137727)
- 3-(1-Naphthoxy)lactic acid (CAS 10476-54-7)
- 1-Ethyl-1-methyl-1-pyrrolidinium Bromide (CAS 69227-51-6)
- 3-(3,4,5-triethoxybenzoyl)-1,3-thiazolidine-2-thione (CAS 1092332-54-1)
- Semaglutide Impurity 146 (CAS 2645421-68-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com