5,7-Dimethyl-[1,3]thiazolo[4,5-b]pyridin-2-amine CAS 203380-78-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5,7-Dimethyl-[1,3]thiazolo[4,5-b]pyridin-2-amine.

5,7-Dimethyl-[1,3]thiazolo[4,5-b]pyridin-2-amine (CAS 203380-78-3), molecular formula C8H9N3S and molecular weight 179.24 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 5,7-Dimethyl-[1,3]thiazolo[4,5-b]pyridin-2-amine (C8H9N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 179.24 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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