Argatroban Impurity N6 CAS 203383-33-9
| CAS No. | 203383-33-9 |
| Molecular Formula | C16H20N6O6S |
| Molecular Weight | 424.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Argatroban Impurity N6 is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Argatroban Impurity N6 (CAS 203383-33-9) is a certified pharmaceutical impurity reference standard with the molecular formula C16H20N6O6S and a molecular weight of 424.43 g/mol.
Based on its molecular formula C16H20N6O6S, Argatroban Impurity N6 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 424.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H20N6O6S |
| Molecular Weight | 424.43 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2015 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Argatroban Standards
- Argatroban Impurity 71 (CAS CATO-C4X-100771)
- Argatroban Impurity 90 (CAS CATO-C4X-100790)
- Argatroban Impurity 89 (CAS CATO-C4X-100789)
- Argatroban Impurity 91 (CAS CATO-C4X-100791)
- Argatroban Impurity 98 (CAS CATO-C4X-100798)
- Argatroban Impurity 97 (CAS CATO-C4X-100797)
- Argatroban Impurity 45 (CAS CATO-C4X-100745)
- Argatroban Impurity 39 (Mixture of Diastereomers) (CAS 184043-01-4)
Recommended Standards
- 4,4'-(Benzo[c][1,2,5]thiadiazole-4,7-diylbis(ethyne-2,1-diyl))dibenzoicacid (CAS 2098914-50-0)
- Ethyl 2-amino-4-(3-nitrophenyl)-5-oxo-4H,5H-thiochromeno[4,3-b]pyran-3-carboxylate (CAS 939889-05-1)
- (E)-3-((5-cyano-2-hydroxy-1,4-dimethyl-6-oxo-1,6-dihydropyridin-3-yl)diazenyl)phenyl benzenesulfonate (CAS 59312-61-7)
- Ethyl 2-amino-4-(4-nitrophenyl)-5-oxo-4H,5H-thiochromeno[4,3-b]pyran-3-carboxylate (CAS 939894-10-7)
- Clofazimine EP Impurity A (CAS 90690-85-0)
- Tofacitinib Impurity 9 (CAS 2250243-18-4)
- Amiodarone Impurity 41 (CAS CATO-C4X-142541)
- L-Albizziine (CAS 1483-07-4)
- 1-(Ethenyloxy)-2-fluorobenzene (CAS 1499988-60-1)
- 1,2,3,4-Tetrahydro-6-isoquinolinol (CAS 14446-24-3)
- 8-Benzyl-4-(3-nitrobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326813-50-6)
- 2-[(4-sulfamoylphenyl)sulfanyl]acetic acid (CAS 575446-72-9)
- Ethyl 3-bromo-6-cyano-2-(difluoromethyl)benzoate (CAS 1805593-89-8)
- Insulin Degludec Impurity 17 (CAS CATO-C4X-215717)
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