Silodosin Impurity 28 CAS 2034998-44-0
| CAS No. | 2034998-44-0 |
| Molecular Formula | C15H23N3O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Silodosin Impurity 28 (CAS 2034998-44-0) is a certified pharmaceutical impurity reference standard with the molecular formula C15H23N3O2HCl and a molecular weight of 313.83 g/mol.
The molecular framework of Silodosin Impurity 28 (C15H23N3O2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C15H23N3O2 HCl |
| Molecular Weight | 313.83 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Silodosin Standards
- Silodosin-d6 (CAS 1051374-52-7)
- Silodosin Impurity 25 (CAS 1096141-53-5)
- Silodosin S-amine Isomer (CAS 1201180-97-3)
- Silodosin Impurity 29 (CAS 1251924-67-0)
- Silodosin-d6 DiHCl (CAS 1261392-62-4)
- Silodosin impurity N1 (CAS 1338365-54-0)
- Silodosin Carboxylic Acid Impurity (CAS 1357252-79-9)
- Silodosin Impurity 20 (CAS 1375180-28-1)
Recommended Standards
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- 2-(3-Chloro-2-methoxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2121513-15-1)
- Gulonic Acid Sodium Salt (CAS 6451-20-3)
- 5-Amino-4-methylpicolinic acid hydrochloride (CAS 2248334-35-0)
- 2-[(3-bromo-4-methoxyphenyl)methyl]-3-hydroxypropanenitrile (CAS 1275190-08-3)
- Dimethyl 2-(bromomethyl)terephthalate (CAS 57834-13-6)
- 4-Chloro-3-cyano-5-ethylbenzene-1-sulfonyl chloride (CAS 1805562-00-8)
- Eledoisin Related Peptide (CAS 2990-43-4)
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