L-Leucine-d3-N-t-BOC H2O (methyl-d3) CAS 203645-42-5

Purity 97%+In StockPharmaceutical Standards
CAS No.203645-42-5
Molecular Formula-
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

L-Leucine-d3-N-t-BOC H2O (methyl-d3) CAS 203645-42-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including L-Leucine-d3-N-t-BOC H2O (methyl-d3).

L-Leucine-d3-N-t-BOC H2O (methyl-d3) (CAS 203645-42-5), molecular formula C11H18D3NO4H2O and molecular weight 252.32 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of L-Leucine-d3-N-t-BOC H2O (methyl-d3) (C11H18D3NO4H2O) is characterized by deuterium isotope labeling, an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H18D3NO4 H2O
Molecular Weight252.32 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)2.5
CAS Registry Year (est.)2015
Nitrogen Atoms1

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Why CATO?