Prednisolone impurity 67 CAS 20380-17-0
| CAS No. | 20380-17-0 |
| Molecular Formula | C21H29BrO3 |
| Molecular Weight | 409.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Prednisolone impurity 67 (CAS 20380-17-0) is a certified pharmaceutical impurity reference standard with the molecular formula C21H29BrO3 and a molecular weight of 409.36 g/mol.
Prednisolone impurity 67 (C21H29BrO3) contains a steroid core, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Prednisolone impurity 67 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H29BrO3 |
| Molecular Weight | 409.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Br-containing |
Related Prednisolone Standards
- Prednisolone impurity 66 (CAS 137759-50-3)
- Prednisolone impurity 68 (CAS CATO-C4X-173768)
- Prednisolone Impurity 42 (CAS 3597-59-9)
- Prednisolone Acetate (CAS 52-21-1)
- Prednisolone 17-Acetate (CAS 52628-64-5)
- Prednisolone Impurity 61 (CAS 50718-16-6)
- Prednisolone Impurity 41 (CAS CATO-C4X-173741)
- Prednisolone impurity 60 (CAS CATO-C4X-173760)
Recommended Standards
- N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(2,2,2-trifluoroethyl)-L-serine (CAS 2642331-52-8)
- Lasmiditan Impurity 46 (CAS CATO-C4X-247846)
- Medroxyprogesterone Acetate Impurity 7 (CAS 28018-91-9)
- 5-Bromo-1-(phenylsulfonyl)-2-(trimethylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1305324-90-6)
- Gemifloxacin impurity 1 (CAS CATO-C4X-27471)
- Selexipag Impurity 5 (CAS 2287345-22-4)
- Cabozantinib Impurity 40 (CAS 1275738-77-6)
- 2,3,6,7-Tetrachlorodibenzo[b,d]thiophene (CAS 133513-19-6)
- 2-Chloro-3-(trifluoromethyl)quinoline-8-carboxylic acid (CAS 590372-14-8)
- 1-(tert-butoxycarbonyl)-3,5-dimethyl-1h-pyrazol-4-ylboronic acid 1-(tert-butoxycarbonyl)pyrazole-4-boronic acid 1-boc-3,5-dimethylpyrazole-4-boronic acid 1-boc-4-pyrazoleboronic acid 1-tert-Butoxycarbonyl-1H-pyrazole-4-boronic acid 1h-pyrazole-4-boronic acid, n-boc protected 947533-31-5 n-boc-1h-pyrazole-4-boronic acid (CAS 947533-31-5)
- 2,3-Diamino-5-(2-hydroxyethyl)-6-methylpyrimidin-4(3H)-one (CAS 95095-45-7)
- (S)-1-(4-Methoxyphenyl)ethanamine hydrochloride (CAS 574744-39-1)
- 1-Bromo-2-isopropyl-4-(methoxymethoxy)benzene (CAS 2635937-09-4)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com