4-Chloro-2-(4,5-dihydro-1H-imidazol-2-yl)isoindoline hydrochloride CAS 204274-74-8
| CAS No. | 204274-74-8 |
| Molecular Formula | C11H12ClN3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Chloro-2-(4,5-dihydro-1H-imidazol-2-yl)isoindoline hydrochloride (C11H12ClN3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 4-Chloro-2-(4,5-dihydro-1H-imidazol-2-yl)isoindoline hydrochloride (CAS 204274-74-8), a certified reference material (molecular formula C11H12ClN3HCl, MW 258.15 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-2-(4,5-dihydro-1H-imidazol-2-yl)isoindoline hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12ClN3 HCl |
| Molecular Weight | 258.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2015 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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- Prilocaine Impurity 57 (CAS CATO-C4X-193457)
- (2E)-N-(4-Bromo-3-methylphenyl)-3-[4-(trifluoromethoxy)phenyl]prop-2-enamide (CAS 882082-62-4)
- 3-Methylcyclopentane-1-sulfonamide (CAS 1341961-86-1)
- Topiramate Impurity 14 (CAS 4136-95-2)
- (3-Cyano-4-(oxetan-3-yl)phenyl)boronic acid (CAS 2256708-83-3)
- N1,N1-Diallylterephthalamide (CAS 73712-25-1)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
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