Vilazodone Impurity 4 CAS 2044702-50-1
| CAS No. | 2044702-50-1 |
| Molecular Formula | C17H16Cl2N2O2 |
| Molecular Weight | 351.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Vilazodone Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Vilazodone Impurity 4 (CAS 2044702-50-1, C17H16Cl2N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Vilazodone Impurity 4 (C17H16Cl2N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H16Cl2N2O2 |
| Molecular Weight | 351.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Vilazodone Standards
- Vilazodone Impurity 2 (CAS CATO-C4X-13552)
- Vilazodone Impurity 5 (CAS 2044706-63-8)
- Vilazodone Impurity 3 (CAS CATO-C4X-13553)
- Vilazodone impurity 16 (CAS 795266-89-6)
- Vilazodone Impurity 42 (CAS 1602487-82-0)
- Vilazodone (CAS 163521-12-8)
- Vilazodone Impurity 13 (CAS 1186225-86-4)
- Vilazodone impurity 01 (CAS 163521-19-5)
Recommended Standards
- (S)-3-(2-Bromo-4-methoxyphenyl)-2-(4-methoxyphenyl)propan-1-ol (|AS)-2-Bromo-4-methoxy-|A-(4-methoxyphenyl)benzenepropanol 917379-11-4 (CAS 917379-11-4)
- 1-[(5-Bromo-2-fluoro-4-methylsulfonyl)phenyl]-homopiperazine (CAS 1020722-22-8)
- N-cyclopentyl-4-(2,6-dichlorobenzoyl)-1H-pyrrole-2-carboxamide (CAS 477870-41-0)
- tert-Butyl 7-bromo-3,4-dihydro-1H-pyrido[4,3-b]indole-2(5H)-carboxylate (CAS 1173155-30-0)
- Chlorphenamine Impurity 26 (CAS CATO-C4X-118826)
- Acetylcysteine Impurity 40 (CAS 25779-79-7)
- Pemetrexed EP Impurity B&C (CAS 1644286-34-9)
- 2-(2-((3-Methoxyphenyl)amino)-2-oxoethoxy)acetic acid (CAS 914630-51-6)
- Tert-butyl 7-(1-hydroxyethyl)-3-azabicyclo[4.1.0]Heptane-3-carboxylate (CAS 2154256-66-1)
- 3-((1-Methyl-1h-imidazol-2-yl)methyl)piperidin-3-ol (CAS 1511867-86-9)
- (5-(Benzyloxy)pyridin-2-yl)methanol (CAS 59781-11-2)
- 4-(Aminomethyl)-5-cyclopropoxy-N-methylnicotinamide (CAS 1243459-14-4)
- 2-(Ethylamino)-2-methylpropanenitrile (CAS 31058-08-9)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
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