Topiroxostat Impurity 24 CAS 2044704-63-2
| CAS No. | 2044704-63-2 |
| Molecular Formula | C7H8N4O2 |
| Molecular Weight | 180.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Topiroxostat Impurity 24.
Topiroxostat Impurity 24 (CAS 2044704-63-2) is a certified pharmaceutical impurity reference standard with the molecular formula C7H8N4O2 and a molecular weight of 180.16 g/mol.
The molecular framework of Topiroxostat Impurity 24 (C7H8N4O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Topiroxostat Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8N4O2 |
| Molecular Weight | 180.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 4 |
Related Topiroxostat Standards
- Topiroxostat Impurity 15 (CAS 87544-86-3)
- Topiroxostat Impurity 31 (CAS CATO-C4X-105531)
- Topiroxostat Impurity 43 (CAS CATO-C4X-105543)
- Topiroxostat Impurity 42 (CAS CATO-C4X-105542)
- Topiroxostat Impurity 78 (CAS CATO-C4X-105578)
- Topiroxostat impurity 75 (CAS CATO-C4X-105575)
- Topiroxostat Impurity 22 (CAS 160601-84-3)
- Topiroxostat Impurity 34 (CAS 2044708-04-3)
Recommended Standards
- Caffeoyl alcohol (CAS 3598-26-3)
- Tofacitinib Impurity 149 (CAS 861612-04-6)
- D-Tagatose (CAS 87-81-0)
- Valproate Impurity 71 (CAS CATO-C4X-116671)
- Fenbufen EP Impurity D (CAS CATO-C4X-19393)
- Pemafibrate Impurity 79 (CAS CATO-C4X-290379)
- Iguratimod Impurity 138 (CAS CATO-C4X-1826138)
- 2-(2,5-Dimethylphenyl)quinoline-4-carboxylic acid (CAS 20389-07-5)
- Ethyl 2-(7-methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)acetate (CAS 145694-86-6)
- 3-(tert-Butyl)pyrazole (CAS 15802-80-9)
- 6-Amino-8-(aminomethyl)-1H-purin-2(3H)-one (CAS 953072-21-4)
- (2',3'-Difluoro-[1,1'-biphenyl]-3-yl)methanamine (CAS 1341956-68-0)
- Methyl 5-chloro-2-ethoxybenzoate (CAS 75230-37-4)
- Anti-Inflammatory Peptide 2 (CAS 118850-72-9)
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