Topiroxostat Impurity 78 CAS CATO-C4X-105578
| CAS No. | CATO-C4X-105578 |
| Molecular Formula | C8H6N4O2 |
| Molecular Weight | 190.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Topiroxostat Impurity 78 (CAS CATO-C4X-105578), a pharmacopoeial impurity reference standard (molecular formula C8H6N4O2, MW 190.16 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Topiroxostat Impurity 78 (C8H6N4O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 190.16 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Topiroxostat Impurity 78 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6N4O2 |
| Molecular Weight | 190.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Topiroxostat Standards
- Topiroxostat impurity 75 (CAS CATO-C4X-105575)
- Topiroxostat Impurity 42 (CAS CATO-C4X-105542)
- Topiroxostat Impurity 43 (CAS CATO-C4X-105543)
- Topiroxostat Impurity 34 (CAS 2044708-04-3)
- Topiroxostat Impurity 31 (CAS CATO-C4X-105531)
- Topiroxostat Impurity 15 (CAS 87544-86-3)
- Topiroxostat Impurity 24 (CAS 2044704-63-2)
- Topiroxostat Impurity 50 (CAS CATO-C4X-105550)
Recommended Standards
- N-Nitroso-2,2-iminodiacetohydrazide (CAS CATO-C3D-26188)
- Brexpiprazole impurity 121 (CAS CATO-C4X-1131121)
- 1,1,1-Trifluoro-2-phenyl-propan-2-ol 1,1,1-trifluoro-2-phenylpropan-2-ol 426-54-0 (CAS 426-54-0)
- Nitroxoline (CAS 4008-48-4)
- Stiripentol Impurity 8 (CAS CATO-C4X-32298)
- Sitagliptin Impurity 64 (CAS 877402-43-2)
- Atropine Impurity 37 (CAS 35721-90-5)
- (R)-1-(tert-butoxycarbonyl)-2-methylpiperidine-2-carboxylic acid (CAS 1415566-32-3)
- 2,3,4,5-Tetrafluoro-6-(methylthio)benzaldehyde (CAS 2773501-85-0)
- （R)-Etomidate EP Impurity B (CAS 61045-91-8)
- 5-((4-Fluorobenzyl)oxy)-4-oxo-N-(3-phenylpropyl)-4H-pyran-2-carboxamide (CAS 1021060-60-5)
- 6-(Benzylthio)-9-(tetrahydrofuran-2-yl)-9H-purin-2-amine (CAS 93312-54-0)
- 1-(3-Hydroxyphenyl)-2,5-dihydro-1h-pyrrole-2,5-dione (CAS 63381-38-4)
- Tau Peptide (268-282) trifluoroacetate salt (CAS 330456-37-6)
Why CATO?
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