(E)-3-(3-chloropyridin-4-yl)acrylic acid CAS 2045276-61-5
| CAS No. | 2045276-61-5 |
| Molecular Formula | C8H6ClNO2 |
| Molecular Weight | 183.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (E)-3-(3-chloropyridin-4-yl)acrylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(E)-3-(3-chloropyridin-4-yl)acrylic acid (CAS 2045276-61-5) is a high-purity analytical reference standard with the molecular formula C8H6ClNO2 and a molecular weight of 183.59 g/mol.
(E)-3-(3-chloropyridin-4-yl)acrylic acid (C8H6ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClNO2 |
| Molecular Weight | 183.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- (2e)-3-(2-Chloropyridin-3-yl)prop-2-enoic acid (CAS 118419-93-5)
- (2E)-3-(5-Chloropyridin-3-yl)prop-2-enoic acid (CAS 118419-97-9)
- (e)-3-(6-Chloropyridin-3-yl)acrylic acid (CAS 118420-00-1)
- 3-(6-chloropyridin-3-yl)prop-2-enoic acid (CAS 1198101-53-9)
- 3-(2-Chloropyridin-4-yl)acrylic acid (CAS 1379423-73-0)
- (E)-3-(2-Chloropyridin-4-yl)acrylic acid (CAS 2045276-63-7)
- 1-(2-Chloropyridin-4-yl)butan-1-one (CAS 113961-70-9)
- 4-(3-Chloropyridin-4-yl)butanal (CAS 1479653-90-1)
Recommended Standards
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- 2-Methoxyphenol-3,4,5,6-d4 (CAS 7329-52-4)
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- FLuorescent brightener 135 (CAS 17233-65-7)
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- Semaglutide impurity 255 (CAS CATO-C4X-2226255)
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