(E)-1-Chloro-4-(2-nitrovinyl)benzene CAS 5153-70-8
| CAS No. | 5153-70-8 |
| Molecular Formula | C8H6ClNO2 |
| Molecular Weight | 183.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
(E)-1-Chloro-4-(2-nitrovinyl)benzene (CAS 5153-70-8) is a high-purity analytical reference standard with the molecular formula C8H6ClNO2 and a molecular weight of 183.59 g/mol.
The molecular framework of (E)-1-Chloro-4-(2-nitrovinyl)benzene (C8H6ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClNO2 |
| Molecular Weight | 183.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- (Z)-1-Chloro-4-(2-nitrovinyl)benzene (CAS 101671-01-6)
- 5-Chloro-3-hydroxyindolin-2-one (CAS 1021047-09-5)
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- 6-Chloro-3-methoxybenzo[d]isoxazole (CAS 1072903-41-3)
- 4-Chloro-1-nitro-2-vinylbenzene (CAS 112768-02-2)
- 5-Chloro-6-methylbenzo[d]oxazol-2(3H)-one (CAS 118794-10-8)
- 7-Chloro-2H-pyrano[2,3-b]pyridin-4(3H)-one (CAS 1196145-79-5)
- 2-Chloro-7-methoxybenzo[d]oxazole (CAS 1202879-56-8)
Recommended Standards
- (E)-1-Chloro-3-(2-nitrovinyl)benzene (CAS 3156-35-2)
- (E)-3-(2-Chloropyridin-4-yl)acrylic acid (CAS 2045276-63-7)
- (E)-1-Chloro-2-(2-nitrovinyl)benzene (CAS 22568-07-6)
- (E)-3-(3-chloropyridin-4-yl)acrylic acid (CAS 2045276-61-5)
- Ethyl 5,6-dihydro-4H-furo[2,3-c]pyrrole-3-carboxylate (CAS 1445951-58-5)
- Azido-PEG8-C-Boc (CAS 1984776-39-7)
- 4,6-Difluoro-1,3-benzoxazol-2-amine (CAS 1339452-03-7)
- Ethyl 4-(3-bromophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate (CAS 338960-00-2)
- 1-((2,5-Dimethoxyphenyl)sulfonyl)-3-methyl-1H-pyrazole (CAS 957311-94-3)
- Atogepant Impurity 67 (CAS CATO-C4X-328567)
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- Liraglutide (CAS 204656-20-2)
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