Carfilzomib Impurity 22 CAS 2049025-45-6

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.2049025-45-6
Molecular FormulaC40H57N5O7
Molecular Weight719.91 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Carfilzomib Impurity 22 CAS 2049025-45-6 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Carfilzomib Impurity 22.

Carfilzomib Impurity 22 (CAS 2049025-45-6) is a certified pharmaceutical impurity reference standard with the molecular formula C40H57N5O7 and a molecular weight of 719.91 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Carfilzomib Impurity 22 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 719.91 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Carfilzomib Impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC40H57N5O7
Molecular Weight719.91 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)15.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1997
Nitrogen Atoms5

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