(R)-4,4'-diiodo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol CAS 2050189-65-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-4,4'-diiodo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol.

(R)-4,4'-diiodo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol (CAS 2050189-65-4), molecular formula C17H14I2O2 and molecular weight 504.10 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a steroid core, a hydroxyl group, an ether linkage, iodine substitution, (R)-4,4'-diiodo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 504.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (R)-4,4'-diiodo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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