Silodosin Depropanol Impurity1 CAS 2052161-47-2
| CAS No. | 2052161-47-2 |
| Molecular Formula | C22H26F3N3O3 |
| Molecular Weight | 437.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 437.46 g/mol gives Silodosin Depropanol Impurity1 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Silodosin Depropanol Impurity1 (CAS 2052161-47-2, C22H26F3N3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Silodosin Depropanol Impurity1 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 437.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Silodosin Depropanol Impurity1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H26F3N3O3 |
| Molecular Weight | 437.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Silodosin Standards
- Silodosin Impurity 6 (CAS 2755910-23-5)
- Silodosin Impurity 15 (CAS 2052161-50-7)
- Silodosin Impurity 5 (CAS CATO-C4X-17545)
- Silodosin Impurity 11 (CAS 239463-74-2)
- Silodosin Impurity 9 (CAS 885340-13-6)
- Silodosin Impurity 7 (CAS 350797-56-7)
- Silodosin Impurity 1 (CAS 175870-21-0)
- Silodosin (CAS 160970-64-9)
Recommended Standards
- Pitavastatin Impurity 87 (CAS 224320-09-6)
- Pitavastatin Impurity 50 (CAS 1980814-87-6)
- ZHC-116 Impurity 9 (CAS CATO-C4X-23889)
- Pitavastatin Impurity 116 (CAS CATO-C4X-1037116)
- Olanzapine Impurity 47 (CAS CATO-C4X-117847)
- Tedizolid Impurity 58 (CAS CATO-C4X-105458)
- Carbetocin Impurity 41 (CAS CATO-C4X-191141)
- 7-(2-Methoxyethyl)-1,3-dimethyl-8-(methylthio)-3,7-dihydro-1H-purine-2,6-dione (CAS 878736-61-9)
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