| CAS No. | 205248-77-7 |
| Molecular Formula | H2NO3S |
| Molecular Weight | 96.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies Topiramate Impurity 3 (CAS 205248-77-7), a certified reference material (molecular formula H2NO3S, MW 96.09 g/mol) for analytical method development and quality control.
The molecular framework of Topiramate Impurity 3 (H2NO3S) is characterized by a sulfone group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
| Molecular Formula | H2NO3S |
| Molecular Weight | 96.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Freely soluble in water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| CAS Registry Year (est.) | 2015 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |