(2R,3S,4R,5R)-2-(6-Amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol CAS 20535-16-4
| CAS No. | 20535-16-4 |
| Molecular Formula | C10H12FN5O4 |
| Molecular Weight | 285.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (2R,3S,4R,5R)-2-(6-Amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(2R,3S,4R,5R)-2-(6-Amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 20535-16-4), molecular formula C10H12FN5O4 and molecular weight 285.23 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (2R,3S,4R,5R)-2-(6-Amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol (C10H12FN5O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 285.23 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H12FN5O4 |
| Molecular Weight | 285.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Recommended Standards
- (2R,3R,4S,5R)-2-(6-Amino-8-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 23205-67-6)
- (2S,3S,4S,5R)-2-(6-Amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 21679-15-2)
- (1-(Benzyloxy)-2-oxopiperidin-3-yl)phosphonic acid (CAS 2004714-48-9)
- 1,3-Dioxoisoindolin-2-yl 4-fluorobenzoate (CAS 305359-06-2)
- Tert-butyl (5-bromobenzo[d]thiazol-2-yl)carbamate (CAS 1160573-06-7)
- 2-(2-Chlorophenyl)piperazine (CAS 793614-34-3)
- 4-Formylfuran-2-sulfonamide (CAS 1444883-75-3)
- 1-(3'-Methoxy[1,1'-biphenyl]-2-yl)ethanone (CAS 893739-12-3)
- 890591-84-1 3-(4-ethylphenyl)-1H-pyrazole-5-carboxylic acid DTXSID10393298 (CAS 890591-84-1)
- (4-Bromophenyl)acetyl chloride (CAS 37859-24-8)
- 1-Methyl-2-oxo-1,2-dihydroquinoline-6-carboxylic acid (CAS 23845-05-8)
- 3,4-Bis(4-methoxyphenyl)-1-(2-methylbenzoyl)-1H-pyrazole (CAS 956796-38-6)
- 3-Amino-2-methyl-N-(3-methylbenzyl)propanamide hydrochloride (CAS 1838990-41-2)
- Prolactin-Releasing Peptide (1-31) (rat) (CAS 215510-06-8)
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