1,3-Dioxoisoindolin-2-yl 4-fluorobenzoate CAS 305359-06-2
| CAS No. | 305359-06-2 |
| Molecular Formula | C15H8FNO4 |
| Molecular Weight | 285.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1,3-Dioxoisoindolin-2-yl 4-fluorobenzoate (CAS 305359-06-2), molecular formula C15H8FNO4 and molecular weight 285.23 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1,3-Dioxoisoindolin-2-yl 4-fluorobenzoate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 285.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H8FNO4 |
| Molecular Weight | 285.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Dioxoisoindolin Standards
- 2-(1,3-Dioxoisoindolin-2-yl)-N-(3-methylisoxazol-5-yl)acetamide (CAS 1049291-84-0)
- 2-(1,3-Dioxoisoindolin-2-yl)-N-(furan-2-ylmethyl)acetamide (CAS 299950-85-9)
- 2-(1,3-Dioxoisoindolin-2-yl)-N-(2,2,2-trifluoroethyl)acetamide (CAS 732294-41-6)
- 1-(2-(1,3-Dioxoisoindolin-2-yl)ethyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1038705-00-8)
- 2-(5-((1,3-Dioxoisoindolin-2-yl)methyl)-1,2,4-oxadiazol-3-yl)acetamide (CAS 1809484-44-3)
- 3-(1,3-Dioxoisoindolin-2-yl)propyl methanesulfonate (CAS 115306-79-1)
- 5-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybenzoic acid (CAS 168903-55-7)
- 4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybenzoic acid (CAS 36467-52-4)
Recommended Standards
- (2S,3S,4S,5R)-2-(6-Amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 21679-15-2)
- 2-(3-Fluorophenyl)-1,3-dioxoisoindoline-5-carboxylic acid (CAS 202264-03-7)
- (2R,3S,4R,5R)-2-(6-Amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 20535-16-4)
- 2-(5-Fluoro-1,3-dioxoisoindolin-2-yl)benzoic acid (CAS 299963-55-6)
- 5-Ethynyl-2-fluorobenzonitrile (CAS 1093306-86-5)
- 5-Chloro-3-cyclopropyl-1,2,4-thiadiazole (CAS 122684-54-2)
- 4-(3-Methoxyphenyl)tetrahydro-2H-pyran-4-amine hydrochloride (CAS 1380300-46-8)
- 2-(4,6-Dichloro-2-Methyl-Phenoxy)-Propionic Acid (CAS 20021-12-9)
- 1-Methyl-1H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione (CAS 5401-15-0)
- N-(3-Chloro-2-(trifluoromethoxy)phenyl)acetamide (CAS 2007916-05-2)
- 2-(1H-1,2,3-Triazol-5-yl)ethanamine (CAS 52845-67-7)
- 2,4,5-Trifluoro-N-methylbenzamide (CAS 1203954-79-3)
- 2-(4-Chlorophenyl)-2-(2,2-dimethylmorpholin-4-yl)acetonitrile (CAS 1258650-80-4)
- Insulin Lispro (CAS 133107-64-9)
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