Nelarabine Impurity 1 CAS 20535-83-5

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.20535-83-5
Molecular FormulaC6H7N5O
Molecular Weight165.15 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Nelarabine Impurity 1 CAS 20535-83-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 165.15 g/mol gives Nelarabine Impurity 1 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Nelarabine Impurity 1 (CAS 20535-83-5) is a certified pharmaceutical impurity reference standard with the molecular formula C6H7N5O and a molecular weight of 165.15 g/mol.

The molecular framework of Nelarabine Impurity 1 (C6H7N5O) is characterized by an amide group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Nelarabine Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC6H7N5O
Molecular Weight165.15 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962
Nitrogen Atoms5

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