Nelarabine Impurity 2 CAS 1173825-84-7
| CAS No. | 1173825-84-7 |
| Molecular Formula | C32H27Cl6N5O5 |
| Molecular Weight | 774.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Nelarabine Impurity 2 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Nelarabine Impurity 2 (CAS 1173825-84-7) is a certified pharmaceutical impurity reference standard with the molecular formula C32H27Cl6N5O5 and a molecular weight of 774.31 g/mol.
Nelarabine Impurity 2 (C32H27Cl6N5O5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C32H27Cl6N5O5 |
| Molecular Weight | 774.31 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Nelarabine Standards
Recommended Standards
- Zinc, [5,10,15,20-tetrakis(4-ethynylphenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]-, (SP-4-1)- (CAS 502613-00-5)
- Methyl 5-Oxopyrrolidin-1-Ide-2-Carboxylate;Rhodium(2+) (CAS 132435-65-5)
- Reactive Blue 5 (CAS 16823-51-1)
- 2,6-Bis(tributylstannyl)dithieno[3,2-b:2',3'-d]thiophene (CAS 944257-56-1)
- Urapidil Impurity 93 (CAS 63987-50-8)
- Dexpanthenol impurity 30 (CAS 10232-92-5)
- Proguanil impurity 1 (CAS CATO-C4X-17391)
- 11,12-Bis[N-methyl-1H-benzimidazolium-3-methylene]-9,10-dihydro-9,10-ethanoanthracene bis(trifluoromethanesulfonate) (CAS 958004-03-0)
- 6-(3-Bromo-4-chlorophenyl)pyridazin-3(2H)-one (CAS 62902-74-3)
- FIPI (CAS 939055-18-2)
- 4,5-Difluoro-1,3-dioxolan-2-one (CAS 171730-81-7)
- Milrinone Impurity 36 (CAS 174966-09-7)
- N-1-Z-1,6-diaminohexane (CAS 66095-18-9)
- Semaglutide Impurity 164 (CAS CATO-C4X-2226164)
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