Efinaconazole Impurity 26 CAS 2055038-63-4
| CAS No. | 2055038-63-4 |
| Molecular Formula | C18H22F2N4O2 |
| Molecular Weight | 364.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Efinaconazole Impurity 26 (CAS 2055038-63-4, C18H22F2N4O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Efinaconazole Impurity 26 (C18H22F2N4O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Efinaconazole Impurity 26 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H22F2N4O2 |
| Molecular Weight | 364.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Efinaconazole Standards
- Efinaconazole Impurity 24 (CAS CATO-C4X-124324)
- Efinaconazole Impurity 32 (CAS CATO-C4X-124332)
- Efinaconazole Impurity 2 (CAS 135133-23-2)
- Efinaconazole-D4 (CAS 164650-44-6 (unlabeled))
- Efinaconazole-d4 (CAS CATO-C4X-124350)
- Efinaconazole Impurity 18 (CAS 2055038-61-2)
- Efinaconazole Impurity 19 (CAS 164650-45-7)
- Efinaconazole Impurity 20 (CAS 2055038-60-1)
Recommended Standards
- rac O-Demethyl Ambrisentan (CAS 1106685-85-1)
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- Tert-butyl2-(4-(benzyloxy)-1-ethoxy-1,3-dioxobutan-2-ylidene)hydrazine-1-carboxylate (CAS 1674398-09-4)
- Phenacetin Impurity 14 (CAS CATO-C4X-204914)
- Mivacurium Chloride Impurity 32 (CAS CATO-C4X-137532)
- Sunitinib Impurity 8 (CAS 251356-82-6)
- 2-Methyl-2-(phenylformamido)propanoic acid (CAS 57224-51-8)
- Efavirenz Related Compound A (CAS 209414-27-7)
- 6-Chloro-2-(chloromethyl)-4(1H)-quinolinone (CAS 946784-67-4)
- 5-Hexyl-4,5-dihydroisoxazole-3-carbaldehyde (CAS 143604-70-0)
- 1-Ethyl-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1047636-01-0)
- 12-Oxotridecanoic acid (CAS 2345-12-2)
- Semaglutide impurity 23 (CAS CATO-C4X-222623)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com