rac 8-Hydroxy Efavirenz CAS 205754-32-1
| CAS No. | 205754-32-1 |
| Molecular Formula | C14H9ClF3NO3 |
| Molecular Weight | 331.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), rac 8-Hydroxy Efavirenz meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
rac 8-Hydroxy Efavirenz (CAS 205754-32-1) is a high-purity analytical reference standard with the molecular formula C14H9ClF3NO3 and a molecular weight of 331.67 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, rac 8-Hydroxy Efavirenz is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 331.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9ClF3NO3 |
| Molecular Weight | 331.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2015 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related rac Standards
- (S)-7-Hydroxy Efavirenz (CAS 252343-24-1)
- ent-8-Hydroxy Efavirenz (CAS 342621-26-5)
- rac 7-Hydroxy Efavirenz (CAS 205754-50-3)
- 8-Hydroxy Efavirenz (~90%) (CAS 205754-33-2)
- 3-Hydroxy Clonazepam (CAS 41993-28-6)
- (S)-3-Hydroxy-1-((S)-4-isopropyl-2-thioxothiazolidin-3-yl)decan-1-one (CAS 1370634-73-3)
- 7-Hydroxy Granisetron-d3 (CAS 133841-15-3(non-labelled))
- 14-Hydroxy-3-methoxy-6-oxo-morphinan 6-Ethylene Ketal (1.0mg/ml in Acetonitrile) (CAS 1612-45-9)
Recommended Standards
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- Methyl 2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)benzoate (CAS 852952-21-7)
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