8-Hydroxy Efavirenz (~90%) CAS 205754-33-2
| CAS No. | 205754-33-2 |
| Molecular Formula | C14H9ClF3NO3 |
| Molecular Weight | 331.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 8-Hydroxy Efavirenz (~90%) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 8-Hydroxy Efavirenz (~90%) (CAS 205754-33-2), a certified reference material (molecular formula C14H9ClF3NO3, MW 331.67 g/mol) for analytical method development and quality control.
Structurally, 8-Hydroxy Efavirenz (~90%) (C14H9ClF3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 331.67 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H9ClF3NO3 |
| Molecular Weight | 331.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2015 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- (S)-7-Hydroxy Efavirenz (CAS 252343-24-1)
- ent-8-Hydroxy Efavirenz (CAS 342621-26-5)
- rac 7-Hydroxy Efavirenz (CAS 205754-50-3)
- rac 8-Hydroxy Efavirenz (CAS 205754-32-1)
- 3-Hydroxy Clonazepam (CAS 41993-28-6)
- (S)-3-Hydroxy-1-((S)-4-isopropyl-2-thioxothiazolidin-3-yl)decan-1-one (CAS 1370634-73-3)
- 7-Hydroxy Granisetron-d3 (CAS 133841-15-3(non-labelled))
- 14-Hydroxy-3-methoxy-6-oxo-morphinan 6-Ethylene Ketal (1.0mg/ml in Acetonitrile) (CAS 1612-45-9)
Recommended Standards
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)benzohydrazide (CAS 1022610-19-0)
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- Methyl 4-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}benzenecarboxylate (CAS 341967-62-2)
- (4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)urea (CAS 339023-79-9)
- 1-(2,4-Difluorophenyl)-2,2-dihydroxyethanone (CAS 1382223-26-8)
- 4-Bromo-2-(difluoromethyl)-3-methoxy-5-nitropyridine (CAS 1807028-79-0)
- 10-Cyclopropyl-1-(9H-fluoren-9-yl)-3,6-dioxo-2,9-dioxa-4,7-diazaundecan-11-oic acid (CAS 2414254-47-8)
- Methyl 8-amino-1,2,3,5,6,7-hexahydro-s-indacene-4-carboxylate (CAS 2409127-42-8)
- 3-[1-(3-Chloro-4-fluorobenzoyl)piperidin-4-yl]-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775458-46-2)
- 4-(Difluoromethoxy)benzotrifluoride (CAS 156570-16-0)
- 3-Ethyl-4-(3-fluorophenyl)-1h-pyrazol-5-amine (CAS 2168913-98-0)
- Dimethyl 3,3'-((4-methoxybenzyl)azanediyl)dipropanoate (CAS 1189373-23-6)
- 1-(5-Amino-1-propyl-1H-benzo[d]imidazol-2-yl)ethan-1-ol (CAS 947013-14-1)
- D-Leu14-Tirzepatide (CAS CATO-CPTD788920)
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