Brexpiprazole Impurity 47 CAS 2060029-80-1
| CAS No. | 2060029-80-1 |
| Molecular Formula | C26H27ClN2O4 |
| Molecular Weight | 466.96 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 466.96 g/mol gives Brexpiprazole Impurity 47 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Brexpiprazole Impurity 47 (CAS 2060029-80-1, C26H27ClN2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Brexpiprazole Impurity 47 (C26H27ClN2O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Brexpiprazole Impurity 47 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H27ClN2O4 |
| Molecular Weight | 466.96 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Brexpiprazole Standards
- Brexpiprazole impurity 106 (CAS 2247155-47-9)
- Brexpiprazole Impurity 48 (CAS 2059942-13-9)
- Brexpiprazole Impurity 65 (CAS 2247155-48-0)
- Brexpiprazole Impurity 74 (CAS CATO-C4X-113174)
- Brexpiprazole Impurity 55 (CAS CATO-C4X-113155)
- Brexpiprazole Impurity 34 (CAS 2247155-42-4)
- Brexpiprazole Impurity 56 (CAS 1191900-59-0)
- Brexpiprazole Impurity 88 (CAS CATO-C4X-113188)
Recommended Standards
- N-((5-((3-Chlorobenzyl)thio)-1,3,4-oxadiazol-2-yl)methyl)-4-(N,N-dimethylsulfamoyl)benzamide (CAS 941985-72-4)
- 2-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluoro-4-methylphenyl)acetamide (CAS 477330-91-9)
- Lipoxamycin hemisulfate (CAS 11075-87-9)
- Tolvaptan Impurity 96 (CAS 1587638-01-4)
- Ketoprofen Impurity N6 (CAS 1257296-76-6)
- Amisulpride impurity 49 (CAS CATO-C4X-104549)
- Crisaborole impurity 159 (CAS CATO-C4X-2021159)
- 1-Bromo-2-difluoromethoxy-3-(trifluoromethoxy)benzene (CAS 1805519-82-7)
- 2-[5-Amino-3-(thiophen-2-yl)-1H-pyrazol-1-yl]-3,4,5,6,7,8-hexahydroquinazolin-4-one (CAS 1206997-36-5)
- (3S,4S)-4-[(1R)-Phenylethylamino-3-methoxycarbonyl]-2,2,6,6-tetramethylpiperidine-1-oxyl Hydrochloride (CAS 583827-06-9)
- 2-(3-Fluorophenyl)benzo[d]oxazole-5-carboxamide (CAS 1706442-86-5)
- tert-Butyl (S)-2-(formamidomethyl)pyrrolidine-1-carboxylate (CAS 1245908-77-3)
- 2-Methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-8-carboxylic acid (CAS 1513705-41-3)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com