Brexpiprazole Impurity 74 CAS CATO-C4X-113174
| CAS No. | CATO-C4X-113174 |
| Molecular Formula | C26H27ClN2O4 |
| Molecular Weight | 466.96 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Brexpiprazole Impurity 74.
Brexpiprazole Impurity 74 (CAS CATO-C4X-113174) is a certified pharmaceutical impurity reference standard with the molecular formula C26H27ClN2O4 and a molecular weight of 466.96 g/mol.
Brexpiprazole Impurity 74 (C26H27ClN2O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H27ClN2O4 |
| Molecular Weight | 466.96 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Brexpiprazole Standards
- Brexpiprazole impurity 106 (CAS 2247155-47-9)
- Brexpiprazole Impurity 47 (CAS 2060029-80-1)
- Brexpiprazole Impurity 48 (CAS 2059942-13-9)
- Brexpiprazole Impurity 65 (CAS 2247155-48-0)
- Brexpiprazole Impurity 55 (CAS CATO-C4X-113155)
- Brexpiprazole Impurity 34 (CAS 2247155-42-4)
- Brexpiprazole Impurity 56 (CAS 1191900-59-0)
- Brexpiprazole Impurity 88 (CAS CATO-C4X-113188)
Recommended Standards
- Tolvaptan Impurity 96 (CAS 1587638-01-4)
- Ribociclib Impurity 19 (CAS CATO-C4X-310019)
- Clobetasol Propionate EP Impurity C (CAS 25122-52-5)
- Clobetasol Propionate (CAS 25122-46-7)
- Imidafenacin Impurity 7 (CAS 214777-44-3)
- Ibuprofen EP Impurity H (CAS 2143535-25-3)
- Lefamulinum Impurity 27 (CAS CATO-C4X-304727)
- Esomeprazole Impurity 40 (CAS 86604-80-0)
- 5-Bromo-2-cyclopropylisoindoline (CAS 1392147-82-8)
- Imidocarb (CAS 27885-92-3)
- 3-({[(tert-butoxy)carbonyl]amino}methyl)-1-methyl-1H-pyrazole-5-carboxylic acid (CAS 1824147-46-7)
- N-Ethyl 4-(aminomethyl)benzamide (CAS 777055-55-7)
- 1-(3,5-Dibromo-2-hydroxyphenyl)ethanone (CAS 22362-66-9)
- Eledoisin Related Peptide (CAS 2990-43-4)
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