1-(pyridin-2-yl)-3-(trifluoromethyl)pyrrolidine-3-carboxylic acid CAS 2060063-50-3
| CAS No. | 2060063-50-3 |
| Molecular Formula | C11H11F3N2O2 |
| Molecular Weight | 260.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 260.21 g/mol gives 1-(pyridin-2-yl)-3-(trifluoromethyl)pyrrolidine-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(pyridin-2-yl)-3-(trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 2060063-50-3), molecular formula C11H11F3N2O2 and molecular weight 260.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(pyridin-2-yl)-3-(trifluoromethyl)pyrrolidine-3-carboxylic acid (C11H11F3N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(pyridin-2-yl)-3-(trifluoromethyl)pyrrolidine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11F3N2O2 |
| Molecular Weight | 260.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 1-(4-Trifluoromethoxy-phenyl)-piperazin-2-one (CAS 790195-84-5)
- 1-[4-Nitro-2-(trifluoromethyl)phenyl]pyrrolidine (CAS 330177-40-7)
- 1-(4-Ethoxyphenyl)-4,4,4-trifluorobutane-1,3-dione (CAS 71712-85-1)
- 1-{[4-(trifluoromethoxy)phenyl]methyl}cyclopropane-1-carboxylic acid (CAS 29765-49-9)
- 3-Bromo-4'-methyl-1,1'-biphenyl (CAS 844856-52-6)
- (R)-1-(3,5-bis(trifluoromethyl)phenyl)propan-2-ol (CAS 1432620-18-2)
- 3-(2,4,5-Trimethoxyphenyl)propanoic acid (CAS 125438-30-4)
- 2,4-Dichloro-7,8-dihydro-[1,4]dioxino[2,3-g]quinazoline (CAS 20197-82-4)
- N-(4-fluoro-2-methylbenzyl)ethanamine (CAS 1248091-26-0)
- 3-(2,6-Dichlorophenyl)-N-(6-methoxypyridin-3-yl)-5-methylisoxazole-4-carboxamide (CAS 883043-28-5)
- 2-(4-((Cyclopentylthio)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2246900-40-1)
- 2-Bromo-5-methoxyquinoline (CAS 1421517-81-8)
- 1,1-Dioxido-2,3-dihydro-4H-thieno[2,3-b]thiopyran-4-yl thiophene-2-carboxylate (CAS 343373-83-1)
- Liraglutide(3-31)TFA Salt (CAS CATO-C4X-19921)
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