3-Amino-1-[2-chloro-5-(trifluoromethyl)phenyl]thiourea CAS 206559-51-5
| CAS No. | 206559-51-5 |
| Molecular Formula | C8H7ClF3N3S |
| Molecular Weight | 269.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Amino-1-[2-chloro-5-(trifluoromethyl)phenyl]thiourea (CAS 206559-51-5) is a high-purity analytical reference standard with the molecular formula C8H7ClF3N3S and a molecular weight of 269.67 g/mol.
3-Amino-1-[2-chloro-5-(trifluoromethyl)phenyl]thiourea (C8H7ClF3N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Amino-1-[2-chloro-5-(trifluoromethyl)phenyl]thiourea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7ClF3N3S |
| Molecular Weight | 269.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2016 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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- 5-Isopropyl-2-methylbenzo[b]thiophene-3-sulfonamide (CAS 1384428-18-5)
- 2-(2,6-Dichlorophenyl)-1H-imidazo[4,5-c]pyridine (CAS 1283261-83-5)
- 1-(3-methoxy-4-propoxyphenyl)ethan-1-amine (CAS 953714-01-7)
- 3,4-Dichloro-5-fluoromandelic acid (CAS 1803827-18-0)
- Peptide 440 (CAS CATO-CPTD788440)
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