4-Chloro-2-fluoro-5-((4-fluorobenzyl)oxy)aniline CAS 453557-77-2
| CAS No. | 453557-77-2 |
| Molecular Formula | C13H10ClF2NO |
| Molecular Weight | 269.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-2-fluoro-5-((4-fluorobenzyl)oxy)aniline (CAS 453557-77-2), molecular formula C13H10ClF2NO and molecular weight 269.67 g/mol, is a CATO reference standard with documented purity and traceability.
4-Chloro-2-fluoro-5-((4-fluorobenzyl)oxy)aniline (C13H10ClF2NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Chloro-2-fluoro-5-((4-fluorobenzyl)oxy)aniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H10ClF2NO |
| Molecular Weight | 269.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-(((2,4-difluorophenyl)amino)methyl)phenol (CAS 1019514-06-7)
- 4-Chloro-2-(((3,4-difluorophenyl)amino)methyl)phenol (CAS 1019547-21-7)
- 2-Chloro-N-(4-((trifluoromethyl)thio)phenyl)acetamide (CAS 1024136-80-8)
- 1-(6-Chloro-4-trifluoromethyl-pyridin-2-yl)-3-methyl-thiourea (CAS 1311278-36-0)
- 4-Chloro-2-(((2,5-difluorophenyl)amino)methyl)phenol (CAS 329777-78-8)
- Ethyl 1-(2-chloro-2,2-difluoroacetyl)piperidine-4-carboxylate (CAS 454473-81-5)
- N-(2-Chloro-5-(trifluoromethyl)phenyl)-2-mercaptoacetamide (CAS 217317-33-4)
- N-(4-Chloro-3-(trifluoromethyl)phenyl)hydrazinecarbothioamide (CAS 38901-30-3)
Recommended Standards
- 3-Amino-1-[2-chloro-5-(trifluoromethyl)phenyl]thiourea (CAS 206559-51-5)
- 4-[(4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-5-methylisoxazole-3-carboxylic acid (CAS 1006455-02-2)
- N-(6-acetylbenzo[d][1,3]dioxol-5-yl)-2-chloropropanamide (CAS 1024126-61-1)
- 4-(6-Chloropyridin-3-yl)-3-methyl-2,4-dioxobutyl acetate (CAS 1174985-78-4)
- 2-(Tetrahydro-2H-pyran-4-yl)pyrazolo[1,5-a]pyrimidin-6-amine (CAS 1478676-26-4)
- 2-[4-(1H-Pyrrol-1-yl)phenoxy]pyrimidine (CAS 339104-69-7)
- 5’-Hydroxy Thalidomide (CAS 203450-07-1)
- Vonoprazan Fumarate Impurity 79 (CAS CATO-C4X-102079)
- 5-(Benzenesulfonyl)-4-methoxy-2-phenylpyrimidine (CAS 478247-27-7)
- 2-(Ethylsulfonyl)-1-(4-fluorophenyl)ethanamine (CAS 1487970-59-1)
- (4-Bromo-2-ethoxy-6-fluorophenyl)boronic acid (CAS 1315340-56-7)
- 3-(4-Hydroxyphenyl)oxetan-3-ol (CAS 1379812-10-8)
- N-(3-(tert-butyl)-2-methyl-4-oxo-2,4-dihydroindeno[1,2-c]pyrazol-6-yl)-2,2,2-trifluoroacetamide (CAS 1024223-97-9)
- (Des-Bromo)-Neuropeptide B (1-23) (human) (CAS 434897-64-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com