Acotiamide Impurity 5 CAS 206882-15-7
| CAS No. | 206882-15-7 |
| Molecular Formula | C12H22N4OS |
| Molecular Weight | 270.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Acotiamide Impurity 5 (C12H22N4OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 270.39 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Acotiamide Impurity 5 (CAS 206882-15-7, C12H22N4OS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Acotiamide Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H22N4OS |
| Molecular Weight | 270.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2016 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Acotiamide Standards
- Acotiamide Impurity 30 (CAS CATO-C4X-111430)
- Acotiamide Impurity 25 (CAS 163936-30-9)
- Acotiamide Impurity 42 (CAS 20029-76-9)
- Acotiamide related compound 4 (CAS 53811-44-2)
- Acotiamide Impurity 19 (CAS CATO-C4X-111419)
- Acotiamide Impurity 4 (CAS 1809272-85-2)
- Acotiamide Impurity 3 (CAS 1824734-16-8)
- Acotiamide Impurity 2 (CAS 490-64-2)
Recommended Standards
- Ticagrelor impurity 102 (CAS CATO-C4X-1093102)
- Promethazine EP Impurity C (CAS 37707-23-6)
- Promethazine EP Impurity C (R-Isomer) (CAS CATO-C3D-262692)
- Piperazine Impurity 4 (CAS 1293489-64-1)
- (R)-Modafinil EP Impurity A (CAS 112111-45-2)
- Upadacitinib Impurity 60 (CAS 2650489-62-4)
- Dotinurad Impurity 254 (CAS CATO-C4X-2494254)
- Rasagiline Impurity 52 (CAS 113535-01-6)
- 1-Cyclopropylguanidine acetate (CAS 1559064-05-9)
- 2-Amino-N-(3,4-dichlorobenzyl)-N-ethylacetamide (CAS 1353982-68-9)
- tert-butyl 4-(3-chloropyridin-2-yl)piperazine-1-carboxylate (CAS 683240-45-1)
- (3R,4S)-4-aminooxan-3-ol (CAS 1096770-58-9)
- N-(3-Bromophenyl)methanesulfonamide (CAS 83922-51-4)
- Insulin Degludec Impurity 16 (CAS CATO-C4X-215716)
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