(R)-Modafinil EP Impurity A CAS 112111-45-2

Description

Compared with other compounds in its class, the molecular weight of 274.33 g/mol gives (R)-Modafinil EP Impurity A distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies (R)-Modafinil EP Impurity A (CAS 112111-45-2), a pharmacopoeial impurity reference standard (molecular formula C15H14O3S, MW 274.33 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system, (R)-Modafinil EP Impurity A is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 274.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), (R)-Modafinil EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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