Canagliflozin Impurity 17 CAS 2069934-29-6
| CAS No. | 2069934-29-6 |
| Molecular Formula | C15H14Cl2O |
| Molecular Weight | 281.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Canagliflozin Impurity 17 is closely related to a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Canagliflozin Impurity 17 (CAS 2069934-29-6, C15H14Cl2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Canagliflozin Impurity 17 (C15H14Cl2O) is characterized by a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H14Cl2O |
| Molecular Weight | 281.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
Related Canagliflozin Standards
- Canagliflozin Impurity 70 (CAS CATO-C4X-112370)
- Canagliflozin Impurity 72 (CAS CATO-C4X-112372)
- Canagliflozin Impurity 73 (CAS CATO-C4X-112373)
- Canagliflozin Impurity 74 (CAS CATO-C4X-112374)
- Canagliflozin Impurity 31 (CAS 2005454-69-1)
- Canagliflozin Impurity 79 (CAS 2265214-90-0)
- Canagliflozin Impurity 4 (CAS CATO-C4X-11234)
- Canagliflozin Impurity 71 (CAS 1662702-88-6)
Recommended Standards
- rel-(1R,2S)-1,2-Bis(4-chlorophenyl)ethane-1,2-diamine (CAS 74641-30-8)
- N,N-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-3-carboxamide (CAS 2377610-18-7)
- Meclozine Impurity 2 (CAS 5321-46-0)
- Cloperastine Impurity 5 (CAS 75842-85-2)
- Darunavir impurity 33 (CAS CATO-C4X-160633)
- Phentolamine Impurity 15 (CAS CATO-C4X-224715)
- Emedastine Impurity 48 (CAS CATO-C4X-226748)
- 5-methyl-1-(pyridin-4-ylmethyl)-1H-1,2,3-triazol-4-amine dihydrochloride (CAS 1803599-13-4)
- (1R,2R,3r,8S)-1-(bromomethyl)cubane (CAS 135191-72-9)
- (+/-)-12-Oxodihydrophytodienoic acid (+/-)-OPC 8 136845-14-2 3-oxo-2(2'[Z]-pentenyl)-cyclopentane-1-hexanoic acid Cyclopentaneoctanoic acid, 3-oxo-2-(2-pentenyl)-, [1alpha,2alpha(Z)]-(?)- Cyclopentaneoctanoic acid, 3-oxo-2-(2Z)-2-pentenyl-, (1R,2R)-rel- (9CI) OPC 8 cyclopentaneoctanoic acid, 3-oxo-2-[(2Z)-2-pentenyl]-, (1R,2R)- (CAS 136845-14-2)
- 4-(Cyclobutylmethoxy)pyridine-3-carboxylic acid (CAS 1439896-51-1)
- 2-(Diphenylphosphoryl)-N,N-diphenylacetamide (CAS 90185-35-6)
- 2-((5-Cyano-[2,3'-bipyridin]-6-yl)thio)-N-(5-methylisoxazol-3(2H)-ylidene)acetamide (CAS 488733-15-9)
- Liraglutide Impurity 16 TFA Salt (CAS CATO-C4X-199216)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com