1-(4-Hydroxy-3-methoxy-5-nitrophenyl)ethanone CAS 20716-41-0
| CAS No. | 20716-41-0 |
| Molecular Formula | C9H9NO5 |
| Molecular Weight | 211.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(4-Hydroxy-3-methoxy-5-nitrophenyl)ethanone (CAS 20716-41-0), molecular formula C9H9NO5 and molecular weight 211.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(4-Hydroxy-3-methoxy-5-nitrophenyl)ethanone (C9H9NO5) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 1-(4-Hydroxy-3-methoxy-5-nitrophenyl)ethanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9NO5 |
| Molecular Weight | 211.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- 1-(2-Hydroxy-4-methoxy-5-nitrophenyl)ethanone (CAS 102877-53-2)
- Methyl 3-hydroxy-2-methyl-4-nitrobenzoate (CAS 1031359-53-1)
- Ethyl 4-hydroxy-2-nitrobenzoate (CAS 104356-27-6)
- Methyl 4-Hydroxy-2-methyl-5-nitrobenzoate (CAS 1163281-04-6)
- 3-Hydroxy-4-[(methoxycarbonyl)amino]benzoic acid (CAS 1183828-26-3)
- 2-Hydroxy-3,4-dimethyl-5-nitrobenzoic acid (CAS 1245529-08-1)
- Methyl 3-hydroxy-4-methyl-5-nitrobenzoate, 97% (CAS 125229-13-2)
- 1-(4-Hydroxy-3-methoxy-2-nitrophenyl)ethan-1-one (CAS 1260785-45-2)
Recommended Standards
- 1-(2,4-Difluorophenyl)-3-methyl-1H-1,2,4-triazol-5(4H)-one (CAS 90208-65-4)
- 1-(4-Hydroxy-5-methoxy-2-nitrophenyl)ethanone (CAS 418759-58-7)
- 1-((4-Nitrobenzyl)oxy)urea (CAS 31150-87-5)
- 1-(BENZO[D][1,3]DIOXOL-6-YL)-2-NITROETHANOL (CAS 40288-64-0)
- Desoximetasone EP Impurity H (CAS 52092-65-6)
- Fmoc-3-iodo-L-phenylalanine (CAS 210282-31-8)
- 1-Methyl-2-nitro-3-(trifluoromethyl)benzene (CAS 92891-23-1)
- Cetirizine Impurity 34 (CAS CATO-C4X-158234)
- (6-Amino-5-chloro-3-(difluoromethyl)pyridin-2-yl)methanol (CAS 1806806-84-7)
- 2-[(5-Bromo-3-methyl-2-pyridinyl)amino]-2-methyl-1-propanol (CAS 1220037-47-7)
- 3-Methyl-1-(m-tolyl)-1H-pyrazol-5-ol (CAS 2235-75-8)
- 2,3-Dihydrobenzofuran-5-sulfonamide (CAS 112894-47-0)
- 3-Chloro-4-methyl-2-(methylthio)phenylboronic acid (CAS 2121513-73-1)
- TRAF6 Control Peptide trifluoroacetate salt (CAS 852690-80-3)
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