(3E)-3-[(3-Fluorophenyl)methylidene]-3,4-dihydro-2H-1-benzopyran-4-one CAS 207442-39-5
| CAS No. | 207442-39-5 |
| Molecular Formula | C16H11FO2 |
| Molecular Weight | 254.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies (3E)-3-[(3-Fluorophenyl)methylidene]-3,4-dihydro-2H-1-benzopyran-4-one (CAS 207442-39-5), a certified reference material (molecular formula C16H11FO2, MW 254.26 g/mol) for analytical method development and quality control.
The molecular framework of (3E)-3-[(3-Fluorophenyl)methylidene]-3,4-dihydro-2H-1-benzopyran-4-one (C16H11FO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H11FO2 |
| Molecular Weight | 254.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2016 |
| Halogen Content | F-containing |
Related E Standards
- 4-(3-Fluorophenyl)-7-methyl-2H-chromen-2-one (CAS 1044277-06-6)
- 2-(3-(4-Fluorophenyl)-1H-1,2,4-triazol-5-yl)aniline (CAS 104615-61-4)
- 2-(3-Fluorophenyl)-8-methylimidazo[1,2-a]pyridine-3-carbaldehyde (CAS 1048917-19-6)
- 2-(3-Fluorophenyl)-7-methylimidazo[1,2-a]pyridine-3-carbaldehyde (CAS 1048917-29-8)
- 2-(3-Fluorophenyl)-6-methylimidazo[1,2-a]pyridine-3-carbaldehyde (CAS 1048917-44-7)
- 4-(4-Fluorophenyl)-3-phenylisoxazol-5-amine (CAS 1092286-97-9)
- 3-(4-fluorophenyl)-4-phenyl-1,2-oxazol-5-amine (CAS 1092288-09-9)
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Recommended Standards
- (3AR,8aS)-2-(5-fluoropyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole (CAS 2757083-57-9)
- (3-Phenyl-allyl)-phosphonicaciddiethylester (CAS 58922-31-9)
- (2E)-3-(4-Fluorophenyl)-2-[(E)-1-methyl-1H-pyrrole-2-carbonyl]prop-2-enenitrile (CAS 900019-53-6)
- (4-Fluorophenyl)(3-methyl-1-benzofuran-2-yl)methanone (CAS 303145-26-8)
- 3,4-Dichloro-5-oxo-2,5-dihydrofuran-2-yl methyl carbonate (CAS 67551-18-2)
- 3-(Hydroxymethyl)-5-methylphenylboronic Acid (CAS 1451391-46-0)
- Methyl 3-oxo-3-(oxolan-2-yl)propanoate (CAS 252366-36-2)
- 6-(3-Hydroxypropyl)benzo[c][1,2]oxaborol-1(3H)-ol (CAS 1268390-57-3)
- Relcovaptan Impurity 1 (CAS 140916-61-6)
- n-Benzyl-6-methylpyridazin-3-amine (CAS 100193-48-4)
- 5-Bromo-8-(dibromomethyl)-7-fluoroquinoline (CAS 2181779-97-3)
- 9-Bromo-8-methoxy-1,2,3,5-tetrahydro-4H-cyclopenta[c]quinolin-4-one (CAS 1338545-80-4)
- Sodium (5-(2-chloro-4-(trifluoromethyl)phenoxy)-2-nitrobenzoyl)(methylsulfonyl)amide (CAS 108731-70-0)
- Insulin Degludec Impurity 19 (CAS CATO-C4X-215719)
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