Linagliptin Impurity 42 CAS 2074688-81-4
| CAS No. | 2074688-81-4 |
| Molecular Formula | C33H32N8O5 |
| Molecular Weight | 620.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Linagliptin Impurity 42 (CAS 2074688-81-4) is a certified pharmaceutical impurity reference standard with the molecular formula C33H32N8O5 and a molecular weight of 620.66 g/mol.
Based on its molecular formula C33H32N8O5, Linagliptin Impurity 42 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 620.66 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C33H32N8O5 |
| Molecular Weight | 620.66 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 8 |
Related Linagliptin Standards
- Linagliptin Impurity 109 (CAS CATO-C4X-1101109)
- Linagliptin impurity 167 (CAS CATO-C4X-1101167)
- Linagliptin impurity 168 (CAS CATO-C4X-1101168)
- Linagliptin Impurity 51 (CAS 886588-63-2)
- Linagliptin Impurity 12 (CAS CATO-C4X-110112)
- Linagliptin Impurity 25 (CAS CATO-C4X-110125)
- Linagliptin Impurity 114 (CAS CATO-C4X-1101114)
- Linagliptin Impurity 86 (CAS CATO-C4X-110186)
Recommended Standards
- (6,7,8,9-Tetrahydrodibenzo[b,d][1,6]dioxecin-1,14-diyl)bis[diphenylphosphine] (CAS 499797-10-3)
- Cefpirome Impurity 39 (CAS CATO-C4X-120739)
- Cathepsin G inhibitor I (CAS 429676-93-7)
- (1R,2S)-1,2-Diphenyl-2-(3-phenylureido)ethyl 2-(diphenylphosphino)benzoate (CAS 2920833-55-0)
- Gadoteridol impurity 35 (CAS 913542-71-9)
- Ticagrelor impurity 104 (CAS CATO-C4X-1093104)
- Deucravacitinib Impurity 16 (CAS 2936652-48-9)
- N1-(2-(3-Fluorophenyl)-2-methoxyethyl)-N2-isopropyloxalamide (CAS 1795455-32-1)
- 2-Imino-10-methyl-3-(phenylsulfonyl)-1-(pyridin-3-ylmethyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 606959-86-8)
- 4-(3-Chloro-4-fluorophenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine (CAS 1189749-85-6)
- Sorafenib Impurity 22 (CAS 583840-03-3)
- (3-Cyclopropyl-5,6-dimethoxypyridin-2-yl)methanamine oxalate (CAS 1956327-76-6)
- 7-Methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ol (CAS 1229622-03-0)
- Semaglutide Impurity 188 (CAS CATO-C4X-2226188)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com