4-Hydroxy-N-(pyrimidin-2-yl)benzenesulfonamide CAS 20778-16-9

Purity 97%+In StockPharmaceutical Standards
CAS No.20778-16-9
Molecular FormulaC10H9N3O3S
Molecular Weight251.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Hydroxy-N-(pyrimidin-2-yl)benzenesulfonamide CAS 20778-16-9 chemical structure

Description

The occurrence of 4-Hydroxy-N-(pyrimidin-2-yl)benzenesulfonamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 4-Hydroxy-N-(pyrimidin-2-yl)benzenesulfonamide (CAS 20778-16-9), a certified reference material (molecular formula C10H9N3O3S, MW 251.26 g/mol) for analytical method development and quality control.

The molecular framework of 4-Hydroxy-N-(pyrimidin-2-yl)benzenesulfonamide (C10H9N3O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H9N3O3S
Molecular Weight251.26 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962
Nitrogen Atoms3
Sulfur Atoms1

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