5-(Bromomethyl)pyrimidine-2,4-diamine hydrobromide CAS 20781-09-3
| CAS No. | 20781-09-3 |
| Molecular Formula | C5H7BrN4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(Bromomethyl)pyrimidine-2,4-diamine hydrobromide (CAS 20781-09-3) is a high-purity analytical reference standard with the molecular formula C5H7BrN4HBr and a molecular weight of 283.95 g/mol.
The molecular framework of 5-(Bromomethyl)pyrimidine-2,4-diamine hydrobromide (C5H7BrN4HBr) is characterized by a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(Bromomethyl)pyrimidine-2,4-diamine hydrobromide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H7BrN4 HBr |
| Molecular Weight | 283.95 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related Bromomethyl Standards
- 5-(Bromomethyl)-2-methyl-4-(trifluoromethyl)thiazole (CAS 1000339-73-0)
- 2-Bromomethyl-5-chloro-1,3-dinitrobenzene (CAS 1000341-01-4)
- 2-(Bromomethyl)-2-butylhexanoic Acid (CAS 100048-86-0)
- 2-(Bromomethyl)-5-(trifluoromethyl)pyridine (CAS 1000773-62-5)
- 4-(bromomethyl)-2-methylbenzonitrile (CAS 1001055-64-6)
- 2-(Bromomethyl)pyridin-3-ol hydrochloride (CAS 1001096-21-4)
- 2-(Bromomethyl)-6-fluoropyridine (CAS 100202-78-6)
- 2-(bromomethyl)-1-oxaspiro[4.4]nonane (CAS 100238-92-4)
Recommended Standards
- (S)-2-Methyl-pyrrolidine 4-Hydroxy-3,4-dihydro-1H-isoquinoline-2-carboxamidine 59335-84-1 (CAS 59335-84-1)
- (S)-1-(2,2-Difluoroethyl)pyrrolidin-3-amine (CAS 1257047-32-7)
- 2-Amino-2-cyclopropylacetic Acid (CAS 15785-26-9)
- 1-phenylpyrrolidin-3-ol (CAS 90874-96-7)
- (2-Aminophenyl)(piperazin-1-yl)methanone (CAS 91337-65-4)
- Diclofenac sodium Impurity 63 (CAS 1254576-93-6)
- Phenyl(p-tolyl)methanamine hydrochloride (CAS 5267-49-2)
- Difluoromethanesulfonyl fluoride (CAS 1554-47-8)
- 4-(3-Chlorophenyl)-5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (CAS 400076-58-6)
- Peptide Impurity 11 X TFA Salt (CAS CATO-CPTD788811)
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