3-(Hydroxymethyl)-5-(trifluoromethyl)phenylboronic acid CAS 2088638-48-4

Purity 97%+In StockPharmaceutical Standards
CAS No.2088638-48-4
Molecular FormulaC8H8BF3O3
Molecular Weight219.95 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(Hydroxymethyl)-5-(trifluoromethyl)phenylboronic acid CAS 2088638-48-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 219.95 g/mol gives 3-(Hydroxymethyl)-5-(trifluoromethyl)phenylboronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 3-(Hydroxymethyl)-5-(trifluoromethyl)phenylboronic acid (CAS 2088638-48-4), a certified reference material (molecular formula C8H8BF3O3, MW 219.95 g/mol) for analytical method development and quality control.

The molecular framework of 3-(Hydroxymethyl)-5-(trifluoromethyl)phenylboronic acid (C8H8BF3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-(Hydroxymethyl)-5-(trifluoromethyl)phenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H8BF3O3
Molecular Weight219.95 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1997
Halogen ContentF-containing

Related Hydroxymethyl Standards

Recommended Standards

Why CATO?