6-(Trifluoromethyl)pyrido[3,2-d]pyrimidin-4-amine CAS 2089333-95-7
| CAS No. | 2089333-95-7 |
| Molecular Formula | C8H5F3N4 |
| Molecular Weight | 214.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-(Trifluoromethyl)pyrido[3,2-d]pyrimidin-4-amine (CAS 2089333-95-7), molecular formula C8H5F3N4 and molecular weight 214.15 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 6-(Trifluoromethyl)pyrido[3,2-d]pyrimidin-4-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 214.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5F3N4 |
| Molecular Weight | 214.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Trifluoromethyl Standards
- 1-(4-(Trifluoromethyl)phenyl)-1H-tetrazole (CAS 1027510-31-1)
- 3-(Trifluoromethyl)-5-(2-pyridyl)-1,2,4-triazole (CAS 219508-27-7)
- 5-[2-(trifluoromethyl)phenyl]-1h-1,2,3,4-tetrazole (CAS 719274-67-6)
- 5-[3-(Trifluoromethyl)phenyl]-1H-tetrazole (CAS 92712-48-6)
- 5-[4-(Trifluoromethyl)phenyl]tetrazole (CAS 2251-79-8)
- 6-(Trifluoromethyl)pyrido[3,2-d]pyrimidin-2-amine (CAS 2091424-89-2)
- 8-(Trifluoromethyl)imidazo[1,2-a]pyridine-2-carbaldehyde (CAS 1020040-56-5)
- 2-(trifluoromethyl)imidazo[1,2-a]pyridine-8-carbaldehyde (CAS 1033434-50-2)
Recommended Standards
- Diisopropyl hexan-2-ylboronate (CAS 86290-26-8)
- Dodecan-2-ylboronic acid (CAS 3088-79-7)
- Methyl 2-amino-5-fluoro-3-nitrobenzoate (CAS 328547-11-1)
- Methyl 2-Amino-6-fluoro-3-nitrobenzoate (CAS 346691-23-4)
- 6-Amino-1-(o-tolyl)pyrimidine-2,4(1H,3H)-dione (CAS 99844-27-6)
- (Isopropylsulfonyl)benzene (CAS 4238-09-9)
- 4-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine (CAS 306314-93-2)
- 1-tert-Butyl 6a-ethyl hexahydropyrrolo[3,2-b]pyrrole-1,6a(2H)-dicarboxylate (CAS 1250994-55-8)
- Clomipramine HCl EP Impurity A DiHCl (CAS CATO-C4X-12653)
- 2-Methyl-1-(thiazol-2-yl)propan-2-ol (CAS 1523460-29-8)
- 5-Chloro-1-methylimidazole (CAS 872-49-1)
- 80120-03-2 4-(3-Methylphenyl)piperidine--hydrogen chloride (1/1) DTXSID60620369 (CAS 80120-03-2)
- 5H-Indeno[1,2-b]pyridine-5-carboxylic acid (CAS 115623-53-5)
- Ganirelix 1-4 peptide (CAS 208599-57-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com