Metoclopramide Impurity 28 CAS 20896-27-9
| CAS No. | 20896-27-9 |
| Molecular Formula | C9H10ClNO3 |
| Molecular Weight | 215.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Metoclopramide Impurity 28 (C9H10ClNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Metoclopramide Impurity 28 (CAS 20896-27-9), a pharmacopoeial impurity reference standard (molecular formula C9H10ClNO3, MW 215.63 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Metoclopramide Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H10ClNO3 |
| Molecular Weight | 215.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Metoclopramide Standards
- Metoclopramide-related Impurity (CAS 121048-67-7)
- Metoclopramide Impurity 103 (CAS CATO-C4X-1415103)
- Metoclopramide Impurity 24 (CAS 55304-05-7)
- Metoclopramide Impurity 37 (CAS 184151-07-3)
- Metoclopramide Impurity 38 (CAS CATO-C4X-141538)
- Metoclopramide Impurity 39 (CAS 81887-68-5)
- Metoclopramide Impurity 40 (CAS 4093-28-1)
- Metoclopramide Impurity 26 (CAS CATO-C4X-141526)
Recommended Standards
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- Rupatadine impurity 1 (CAS 1118754-56-5)
- Clozapine EP Impurity A (CAS 50892-62-1)
- Ceftazidime Impurity 14 (CAS CATO-C4X-121214)
- (E)-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethan-1-one oxime (CAS 7357-12-2)
- 4-Acetylnicotinonitrile (CAS 1211528-85-6)
- 3-(8-(Methylamino)imidazo[1,2-a]pyrazin-3-yl)benzoic acid (CAS 787590-89-0)
- 1-Ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 3832-97-1)
- 5-Bromo-3,4-dimethyl-9H-xanthen-9-one (CAS 1035912-43-6)
- Heptapeptide-6 (CAS CATO-CPTD788823)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com