Rupatadine impurity 1 CAS 1118754-56-5
| CAS No. | 1118754-56-5 |
| Molecular Formula | C7H7Br2N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Rupatadine impurity 1 is closely related to a nitrile group, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Rupatadine impurity 1 (CAS 1118754-56-5) is a certified pharmaceutical impurity reference standard with the molecular formula C7H7Br2NHBr and a molecular weight of 345.86 g/mol.
The molecular framework of Rupatadine impurity 1 (C7H7Br2NHBr) is characterized by a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Rupatadine impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H7Br2N HBr |
| Molecular Weight | 345.86 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Rupatadine Standards
- Rupatadine Impurity 21 (CAS 1007089-84-0)
- Rupatadine Impurity 24 (CAS 100910-66-5)
- Rupatadine Impurity 3 (CAS 102074-19-1)
- Rupatadine impurity 14 (CAS 1210824-61-5)
- Rupatadine EP Impurity C (CAS 1224515-72-3)
- Rupatadine Impurity 4 (CAS 1235342-53-6)
- Rupatadine EP Impurity A (CAS 1354055-68-7)
- Rupatadine Impurity 20 (CAS 1422960-88-0)
Recommended Standards
- Fenbufen EP Impurity A (CAS 17589-68-3)
- Bempedoic Acid Impurity 20 (CAS 2375137-17-8)
- Bupropion impurity 60 (CAS 1193779-48-4)
- 1-(2-((4-Fluorobenzyl)oxy)phenyl)ethan-1-one (CAS 400878-24-2)
- 8-(Trifluoromethyl)isoxazolo[4,3-c]quinolin-3(1H)-one (CAS 1315343-14-6)
- 4-(Difluoromethyl)-3-fluoro-6-methyl-2-(trifluoromethyl)pyridine (CAS 1805525-19-2)
- Procaterol Impurity 8 (CAS CATO-C4X-18108)
- Methyl 4-oxo-4-phenylbut-2-enoate (CAS 14274-07-8)
- 4-(Methylglycyl)piperazine-1-carbaldehyde (CAS 1282097-55-5)
- Semaglutide Impurity 7 (CAS CATO-C4X-22267)
Why CATO?
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