2-(Hydroxymethyl)-5-nitrothiophene CAS 20898-85-5
| CAS No. | 20898-85-5 |
| Molecular Formula | C5H5NO3S |
| Molecular Weight | 159.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 2-(Hydroxymethyl)-5-nitrothiophene (CAS 20898-85-5), a certified reference material (molecular formula C5H5NO3S, MW 159.16 g/mol) for analytical method development and quality control.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, 2-(Hydroxymethyl)-5-nitrothiophene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 159.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H5NO3S |
| Molecular Weight | 159.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Hydroxymethyl Standards
- 5-(Hydroxymethyl)thiazole-2-carboxylic acid (CAS 1244948-87-5)
- 5-(Hydroxymethyl)thiazole-4-carboxylic acid (CAS 188891-43-2)
- 2-(Hydroxymethyl)thiazole-4-carboxylic acid (CAS 221322-09-4)
- 2-(Hydroxymethyl)thiazole-5-carboxylic acid (CAS 59855-88-8)
- Methyl 3-(hydroxymethyl)-1-pyrrolidinecarboxylate (CAS 1247812-12-9)
- 2-(3-(Hydroxymethyl)pyrrolidin-1-yl)acetic acid (CAS 1249584-08-4)
- 1-[2-(hydroxymethyl)morpholin-4-yl]ethan-1-one (CAS 1536993-59-5)
- Methyl 3-(hydroxymethyl)-4,5-dihydroisoxazole-5-carboxylate (CAS 155526-77-5)
Recommended Standards
- 2-(4-Oxo-4,5-dihydrothiazol-2-yl)acetic Acid (CAS 773109-75-4)
- 1-Acetyl-5-fluoro-3-methylpyrrolidin-2-one (CAS 246181-65-7)
- (S)-2-Amino-2-(3-fluorobicyclo[1.1.1]pentan-1-yl)acetic acid (CAS 2020350-39-2)
- 2-(Isoxazol-3-ylthio)acetic acid (CAS 56796-05-5)
- 7-(3,5-Dibromo-1H-1,2,4-triazol-1-yl)heptanenitrile (CAS 1240572-54-6)
- 6,8-Dimethyl-2-phenylquinoline-4-carboxylic Acid (CAS 337496-05-6)
- 3-Methyl-2,6-diphenylimidazo[1,2-b][1,2,4]triazine (CAS 95234-61-0)
- 2-Isopropylisoquinolin-1(2H)-one (CAS 101712-97-4)
- Sofosbuvir Impurity 17 (CAS 1496551-71-3)
- 5-Bromo-N,N,3-trimethylpyrazin-2-amine (CAS 1934508-65-2)
- 1-(Thiophen-3-yl)but-3-en-1-amine hydrochloride (CAS 2268032-38-6)
- tert-Butyl 2-bromo-6-cyano-1H-indole-1-carboxylate (CAS 1881288-64-7)
- Letermovir impurity 109 (CAS CATO-C4X-2915109)
- Immunstimulating Peptide, human (CAS 94773-24-7)
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