8-Bromo-2-(difluoromethyl)quinoline CAS 2091004-29-2
| CAS No. | 2091004-29-2 |
| Molecular Formula | C10H6BrF2N |
| Molecular Weight | 258.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 8-Bromo-2-(difluoromethyl)quinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
8-Bromo-2-(difluoromethyl)quinoline (CAS 2091004-29-2), molecular formula C10H6BrF2N and molecular weight 258.06 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 8-Bromo-2-(difluoromethyl)quinoline (C10H6BrF2N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H6BrF2N |
| Molecular Weight | 258.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 4-Bromo-5,7-difluoro-2-methylquinoline (CAS 1189105-77-8)
- 4-Bromo-5,8-difluoro-2-methylquinoline (CAS 1189105-80-3)
- 4-Bromo-7,8-difluoro-2-methylquinoline (CAS 1189106-60-2)
- 2-Bromo-6-((trifluoromethyl)thio)pyridine (CAS 1204234-28-5)
- 5-bromo-2-[(trifluoromethyl)sulfanyl]pyridine (CAS 1204234-35-4)
- 3-Bromo-5-((trifluoromethyl)thio)pyridine (CAS 1204234-43-4)
- 4-Bromo-2-((trifluoromethyl)thio)pyridine (CAS 1204234-49-0)
- 2-Bromo-5-(trifluoromethylthio)pyridine (CAS 1204234-94-5)
Recommended Standards
- 7-Iodo-1-indanone, 97% (CAS 628732-02-5)
- 8-Iodo-6-methylimidazo[1,2-a]pyridine (CAS 955942-40-2)
- 7-Bromo-2-(difluoromethyl)quinoline (CAS 2091775-45-8)
- Irsogladine Impurity 1 (CAS 30222-00-5)
- tert-Butyl ((1-(2-chloroacetyl)pyrrolidin-2-yl)methyl)carbamate (CAS 1353971-55-7)
- [(3,4-Dimethoxyphenyl)methyl]({[(3,4-dimethoxyphenyl)methyl]sulfamoyl})amine (CAS 337924-32-0)
- 1-(Ethylsulfonyl)-4,4-dimethylpiperidine (CAS 1342244-28-3)
- 2-Chloro-alpha,alpha-dimethyl-benzenepropanal (CAS 278615-09-1)
- [Tyr0] Corticotropin Releasing Factor, human, rat (CAS 100915-92-2)
- 1-(Azocan-1-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one (CAS 28598-08-5)
- Ethyl 1-benzyl-4,4-dimethylpyrrolidine-3-carboxylate (CAS 261896-28-0)
- 1-(2-Bromo-4-fluorobenzyl)-4-methylpiperazine (CAS 1248702-49-9)
- 6-amino-1-methyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione (CAS 142168-90-9)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com