3-Chloro-2-fluoro-5-hydroxypyridine CAS 209328-72-3
| CAS No. | 209328-72-3 |
| Molecular Formula | C5H3ClFNO |
| Molecular Weight | 147.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 147.53 g/mol gives 3-Chloro-2-fluoro-5-hydroxypyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-Chloro-2-fluoro-5-hydroxypyridine (CAS 209328-72-3), a certified reference material (molecular formula C5H3ClFNO, MW 147.53 g/mol) for analytical method development and quality control.
3-Chloro-2-fluoro-5-hydroxypyridine (C5H3ClFNO) contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Chloro-2-fluoro-5-hydroxypyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3ClFNO |
| Molecular Weight | 147.53 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2016 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 5-Chloro-2-fluoropyridin-3-ol (CAS 1003711-65-6)
- 2-Chloro-3-fluoro-4-hydroxypyridine (CAS 1184172-46-0)
- 2-Chloro-5-fluoropyridin-4-ol (CAS 1196153-96-4)
- 6-Chloro-4-fluoropyridin-3-ol (CAS 1211530-63-0)
- 3-Chloro-5-fluoro-4-hydroxypyridine (CAS 1214327-70-4)
- 3-Chloro-5-fluoropyridin-2(1H)-one (CAS 1214345-43-3)
- 3-Chloro-5-fluoropyridine 1-oxide (CAS 1221793-68-5)
- 3-Chloro-2-fluoropyridin-4-ol (CAS 1227499-28-6)
Recommended Standards
- 2-Chloro-5-fluoropyridine 1-oxide (CAS 405230-79-7)
- 5-Chloro-3-fluoro-2-pyridinone (CAS 514797-96-7)
- 2-Chloro-5-fluoropyridin-3-ol (CAS 884494-35-3)
- 2-Chloro-5-fluoropyrimidin-4-amine (CAS 155-10-2)
- 2-Amino-1-(1-methylcyclopropyl)ethan-1-ol (CAS 1526091-58-6)
- 1-Iodo-1-decyne (CAS 67826-81-7)
- 0376AD 1185299-77-7 4-Imidazol-1-yl-butylamine hydrochloride C7H14ClN3 (CAS 1185299-77-7)
- 1-Bromo-4-chloro-2-fluoro-5-methoxybenzene (CAS 146447-18-9)
- N4-(2,3-Dimethylphenyl)-N2-(2-methoxyethyl)-L-asparagine (CAS 1031361-52-0)
- tert-Butyl 4-(1-((benzyloxy)carbonyl)piperidin-4-yl)piperazine-1-carboxylate (CAS 926904-28-1)
- 5-Methyl-2,3-dihydroimidazo[1,2-a]pyridine (CAS 776255-69-7)
- PD153035 hydrochloride, 98% (CAS 183322-45-4)
- 4-Ethoxy-2-(trifluoromethyl)pyrimidine (CAS 24903-68-2)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com