Ethyl 5-(2,4-difluorophenyl)oxazole-2-carboxylate CAS 2095409-33-7
| CAS No. | 2095409-33-7 |
| Molecular Formula | C12H9F2NO3 |
| Molecular Weight | 253.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 5-(2,4-difluorophenyl)oxazole-2-carboxylate (CAS 2095409-33-7) is a high-purity analytical reference standard with the molecular formula C12H9F2NO3 and a molecular weight of 253.20 g/mol.
The molecular framework of Ethyl 5-(2,4-difluorophenyl)oxazole-2-carboxylate (C12H9F2NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H9F2NO3 |
| Molecular Weight | 253.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 1-(3,4-Difluorophenyl)-5-ethyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1096980-54-9)
- 3-{[(2,3-difluorophenyl)methyl]amino}-1h-pyrazole-5-carboxylic acid (CAS 1159940-85-8)
- Ethyl 5-(2,6-Difluorophenyl)isoxazole-3-carboxylate (CAS 1188027-27-1)
- 1-[(2,4-difluorophenyl)methyl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1351847-63-6)
- 3-(5-(2,6-Difluorophenyl)oxazol-2-yl)propanoic acid (CAS 923810-25-7)
- 3-[5-(2,4-difluorophenyl)-1,3-oxazol-2-yl]propanoic acid (CAS 923825-01-8)
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- 6-(2,6-Difluorophenyl)-5-fluoropicolinic acid (CAS 1210419-19-4)
Recommended Standards
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- Ethyl 5,8-difluoro-4-hydroxyquinoline-3-carboxylate (CAS 223690-43-5)
- 5-Cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 438227-80-6)
- Ilexgenin B (CAS 109008-39-1)
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- 3-(Azetidin-1-yl)propanenitrile (CAS 17168-23-9)
- N-(2-Bromobenzyl)-1H-purin-6-amine (CAS 67023-54-5)
- (4-((Furan-2-ylmethoxy)methyl)phenyl)boronic acid (CAS 1256358-66-3)
- 4-Hydroxy-2-(pyridin-2-yl)pyrimidine-5-carboxylic acid (CAS 56406-45-2)
- 3-(2-Fluorophenyl)-2-methoxy-5-(trifluoromethyl)pyridine (CAS 1214374-33-0)
- 4-(3,4-Dimethoxy-2,6-dinitrophenyl)morpholine (CAS 861211-06-5)
- 5-(3-Bromo-4-((4-methylbenzyl)oxy)phenyl)-1,3,4-oxadiazol-2-amine (CAS 1706453-74-8)
- Bax inhibitor peptide V5 (CAS 579492-81-2)
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