Ethyl 5,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate CAS 228728-82-3
| CAS No. | 228728-82-3 |
| Molecular Formula | C12H9F2NO3 |
| Molecular Weight | 253.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 253.20 g/mol gives Ethyl 5,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 5,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 228728-82-3) is a high-purity analytical reference standard with the molecular formula C12H9F2NO3 and a molecular weight of 253.20 g/mol.
Ethyl 5,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate (C12H9F2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ethyl 5,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9F2NO3 |
| Molecular Weight | 253.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2022 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 1-Ethyl-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 101830-83-5)
- Ethyl 6,8-difluoro-4-hydroxyquinoline-3-carboxylate (CAS 107555-38-4)
- Ethyl 6,7-difluoro-4-hydroxyquinoline-3-carboxylate (CAS 111760-35-1)
- Ethyl 6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 121873-01-6)
- 3,4-Difluoro-N-((3-methyl-1,2,4-oxadiazol-5-yl)methyl)benzamide (CAS 1234981-40-8)
- 1-Ethyl-5,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 1267361-62-5)
- 2-((5,8-Difluoro-2-methylquinolin-4-yl)oxy)acetic acid (CAS 1315346-53-2)
- Methyl 6,7-difluoro-4-methoxyquinoline-2-carboxylate (CAS 1325307-24-1)
Recommended Standards
- Ethyl 5-(2,4-difluorophenyl)oxazole-2-carboxylate (CAS 2095409-33-7)
- Ethyl 5,8-difluoro-4-hydroxyquinoline-3-carboxylate (CAS 223690-43-5)
- Ethyl 5-(2,4-Difluorophenyl)isoxazole-3-carboxylate (CAS 934188-80-4)
- ethyl 7,8-difluoro-4-hydroxyquinoline-3-carboxylate (CAS 228728-81-2)
- 2-(3-Bromo-2-chloro-5-(trifluoromethyl)phenyl)acetic acid (CAS 2090523-96-7)
- 4-Bromo-1-butoxy-2-methylbenzene (CAS 287954-84-1)
- Ethyl 2-(3-bromophenyl)-4,4-dimethyl-1,2,3,4-tetrahydroquinoline-6-carboxylate (CAS 1391609-57-6)
- N1,N2-Bis(pyridin-3-ylmethyl)oxalamide (CAS 196491-43-7)
- 4-Methyl-1H-pyrazolo[3,4-b]pyridine (CAS 856859-51-3)
- 6-Chloro-2,3-dimethylbenzoic acid (CAS 5613-24-1)
- 8-Phenyl-1,4-dioxaspiro[4.5]decane-8-carboxylic acid (CAS 51509-99-0)
- (5Z)-5-[(2E)-3-Phenylprop-2-en-1-ylidene]-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 310463-02-6)
- 2-(Difluoromethyl)-6-iodo-5-methylpyridine-3-carboxamide (CAS 1806983-81-2)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
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