Doxofylline Impurity 4 CAS 2095554-12-2
| CAS No. | 2095554-12-2 |
| Molecular Formula | C11H16N4O5 |
| Molecular Weight | 284.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Doxofylline Impurity 4 (CAS 2095554-12-2), a pharmacopoeial impurity reference standard (molecular formula C11H16N4O5, MW 284.27 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C11H16N4O5, Doxofylline Impurity 4 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 284.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C11H16N4O5 |
| Molecular Weight | 284.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 4 |
Related Doxofylline Standards
- Doxofylline Impurity 49 (CAS CATO-C4X-151349)
- Doxofylline Impurity 43 (CAS CATO-C4X-151343)
- Doxofylline-d6 (dimethyl-d6) (CAS 1219805-99-8)
- Doxofylline Impurity 13 (CAS 43135-57-5)
- Doxofylline impurity 44 (CAS CATO-C4X-151344)
- Doxofylline-d4 (CAS 1346599-13-0)
- Doxofylline Impurity 7 (CAS CATO-C4X-15137)
- Doxofylline Impurity 21 (CAS CATO-C4X-151321)
Recommended Standards
- Levosimendan Impurity 14 (CAS CATO-C4X-130814)
- Ribavirin RC 3 (CAS 69313-80-0)
- Riboflavin Impurity 13 (CAS 4250-90-2)
- Phenyl N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)carbamate (CAS 866132-09-4)
- Mianserin Impurity 88 (CAS CATO-C4X-136988)
- Metaraminol Impurity 16 (CAS 37951-47-6)
- Ilaprazole Impurity 154 (CAS CATO-C4X-1130154)
- 2-[2-bromo-5-(2,2,2-trifluoroethoxy)-[1,2,4]triazolo[1,5-a]pyridin-8-yl]propan-2-ol (CAS 2170792-96-6)
- 4-(2,5-Diphenyl-1h-pyrrol-1-yl)benzohydrazide (CAS 112686-44-9)
- (±)5-HETrE (CAS 88053-46-7)
- 2,3,6-Trifluorophenylmethylsulfone (CAS 236739-04-1)
- 3',4'-Difluoro-[1,1'-biphenyl]-4-carbaldehyde (CAS 135862-45-2)
- N-(2-aminoethyl)-2-chlorobenzamide hydrochloride (CAS 94319-83-2)
- Insulin Degludec Impurity 10 (CAS CATO-C4X-215710)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com